Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP11B1 | P15538 | 17/20 | 0.49 |
| ▸ | CYP11B2 | P19099 | 12/20 | 0.46 |
| ▸ | ELANE | P08246 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17156153 | 1.00 | CYP11B1 (0.49) | CYP11B1CYP11B2ELANEGAA | |
| SCHEMBL15722440 | 0.79 | CYP11B1 (0.51) | CYP11B1CYP11B2 | |
| SCHEMBL23581411 | 0.77 | CYP11B1 (0.35) | CYP11B1CYP11B2GAA | |
| SCHEMBL23581410 | 0.77 | CYP11B1 (0.35) | CYP11B1CYP11B2GAA | |
| SCHEMBL23597417 | 0.77 | CYP11B1 (0.35) | CYP11B1CYP11B2GAA | |
| SCHEMBL14224627 | 0.75 | CYP11B1 (0.35) | CYP11B1CYP11B2 | |
| SCHEMBL14021694 | 0.74 | CYP11B1 (0.41) | CYP11B1CYP11B2 | |
| SCHEMBL13871291 | 0.74 | CYP11B1 (0.38) | CYP11B1CYP11B2 | |
| SCHEMBL17156240 | 0.74 | CYP11B1 (0.47) | CYP11B1CYP11B2GAA | |
| SCHEMBL17156241 | 0.74 | CYP11B1 (0.47) | CYP11B1CYP11B2GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2929883-A1 | Pyrazole derivatives as dihydroorotate dehydrogenase (DHODH) inhibitors | INSTITUT PASTEUR (FR) | 2015-10-14 | — | — | EP | disclosed |