Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP11B1 | P15538 | 19/20 | 0.35 |
| ▸ | CYP11B2 | P19099 | 17/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13871291 | 0.89 | CYP11B1 (0.38) | CYP11B1CYP11B2HPGD | |
| SCHEMBL14021474 | 0.84 | CYP11B1 (0.37) | CYP11B1CYP11B2HPGD | |
| SCHEMBL14021694 | 0.78 | CYP11B1 (0.41) | CYP11B1CYP11B2HPGD | |
| SCHEMBL17156152 | 0.75 | CYP11B1 (0.49) | CYP11B1CYP11B2 | |
| SCHEMBL17156153 | 0.75 | CYP11B1 (0.49) | CYP11B1CYP11B2 | |
| SCHEMBL14021461 | 0.70 | CYP11B1 (0.45) | CYP11B1CYP11B2 | |
| SCHEMBL14021457 | 0.68 | CYP11B1 (0.40) | CYP11B1CYP11B2HPGD | |
| SCHEMBL14224631 | 0.67 | TDP1 (0.34) | — | |
| SCHEMBL28693733 | 0.65 | CYP11B1 (0.36) | CYP11B1CYP11B2 | |
| SCHEMBL28410400 | 0.65 | CYP11B1 (0.47) | CYP11B1CYP11B2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080096950-A1 | Compounds Useful In Therapy | PFIZER INC. | 2008-04-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080096950-A1 | Compounds Useful In Therapy | CYP19A1, LPXN, HSD17B11 | CYP11B1 25/4885CYP11B2 12/4885HPGD 7/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.