Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.46 |
| ▸ | HRH3 | Q9Y5N1 | 4/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | GRM5 | P41594 | 7/20 | 0.40 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.40 |
| ▸ | UBE2M | P61081 | 1/20 | 0.40 |
| ▸ | DCUN1D1 | Q96GG9 | 1/20 | 0.40 |
| ▸ | HRH1 | P35367 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Cadaverine Tartrate SCHEMBL15739047 | 0.94 | MEN1 (0.43) | MEN1KMT2AKDM4EPDE4BHRH3 | |
| SCHEMBL3239969 | 0.84 | PDE4B (0.50) | MEN1KMT2AKDM4EPDE4BHRH3 | |
| SCHEMBL17156960 | 0.83 | KDM4E (0.46) | MEN1KMT2AKDM4EPDE4BHRH3 | |
| SCHEMBL17156969 | 0.81 | ALDH1A1 (0.48) | MEN1KMT2AHRH3ALDH1A1 | |
| SCHEMBL17156947 | 0.80 | HRH3 (0.48) | KMT2AKDM4EPDE4BHRH3ALDH1A1 | |
| SCHEMBL17156963 | 0.80 | GRM5 (0.48) | HRH3GRM5 | |
| SCHEMBL17156958 | 0.80 | GRM5 (0.51) | HRH3GRM5 | |
| SCHEMBL17156954 | 0.79 | GRM5 (0.47) | MEN1KMT2AHRH3GRM5KCNH2 | |
| SCHEMBL17156955 | 0.79 | GRM5 (0.50) | HRH3GRM5 | |
| SCHEMBL167877 | 0.78 | HRH3 (0.42) | HRH3GRM5KCNH2HRH1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2611444-B1 | HETEROCYCLYL COMPOUNDS AS HISTAMINE H3 RECEPTOR LIGANDS | SUVEN LIFE SCIENCES LTD (IN) | 2015-10-14 | — | — | EP | claimed |