Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 8/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 8/20 | 0.58 |
| ▸ | MAPT | P10636 | 5/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.58 |
| ▸ | HTT | P42858 | 4/20 | 0.58 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.58 |
| ▸ | GFER | P55789 | 2/20 | 0.58 |
| ▸ | LMNA | P02545 | 2/20 | 0.58 |
| ▸ | THRB | P10828 | 2/20 | 0.58 |
| ▸ | ALPG | P10696 | 1/20 | 0.58 |
| ▸ | RAB9A | P51151 | 7/20 | 0.48 |
| ▸ | NPC1 | O15118 | 5/20 | 0.48 |
| ▸ | GAA | P10253 | 2/20 | 0.48 |
| ▸ | CASP1 | P29466 | 1/20 | 0.48 |
| ▸ | BRCA1 | P38398 | 1/20 | 0.48 |
| ▸ | CASP7 | P55210 | 1/20 | 0.48 |
| ▸ | HBB | P68871 | 1/20 | 0.48 |
| ▸ | APOBEC3A | P31941 | 3/20 | 0.46 |
| ▸ | APOBEC3G | Q9HC16 | 3/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2160671 | 1.00 | MEN1 (0.58) | MEN1KMT2AMAPTSMN1; SMN2HTT | |
| SCHEMBL531127 | 0.81 | MEN1 (0.63) | MEN1KMT2AMAPTSMN1; SMN2HTT | |
| SCHEMBL531126 | 0.81 | MEN1 (0.63) | MEN1KMT2AMAPTSMN1; SMN2HTT | |
| SCHEMBL1402879 | 0.80 | MEN1 (0.58) | MEN1KMT2AMAPTSMN1; SMN2HTT | |
| SCHEMBL9140957 | 0.79 | MEN1 (0.69) | MEN1KMT2AMAPTSMN1; SMN2HTT | |
| SCHEMBL8991523 | 0.79 | MEN1 (0.69) | MEN1KMT2AMAPTSMN1; SMN2HTT | |
| SCHEMBL1898081 | 0.78 | MEN1 (0.96) | MEN1KMT2AMAPTSMN1; SMN2HTT | |
| SCHEMBL1898080 | 0.78 | MEN1 (0.96) | MEN1KMT2AMAPTSMN1; SMN2HTT | |
| Iodide SCHEMBL531167 | 0.76 | MEN1 (1.00) | MEN1KMT2AMAPTSMN1; SMN2HTT | |
| Hydrochloric Acid SCHEMBL28626064 | 0.76 | MEN1 (0.92) | MEN1KMT2AMAPTSMN1; SMN2HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9702870-B2 | Fluorescent dyes and related methods | UNIVERSITY OF WASHINGTON THROUGH ITS CENTER FOR COMMERCIALIZATION (US) | 2017-07-11 | — | — | US | disclosed |
| US-20160313312-A1 | Fluorescent Dyes and Related Methods | UNIVERSITY OF WASHINGTON THROUGH ITS CENTER FOR COMMERCIALIZATION | 2016-10-27 | — | — | US | disclosed |
| US-9410947-B2 | Fluorescent dyes and related methods | UNIVERSITY OF WASHINGTON THROUGH ITS CENTER FOR COMMERCIALIZATION (US) | 2016-08-09 | — | — | US | disclosed |
| US-20150293080-A1 | Fluorescent Dyes and Related Methods | NATIONAL SCIENCE FOUNDATION | 2015-10-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160313312-A1 | Fluorescent Dyes and Related Methods | HNRNPH3, CDC73, EWSR1 | MEN1 3696/4885KMT2A 3128/4885MAPT 3630/4885 |
| US-20150293080-A1 | Fluorescent Dyes and Related Methods | CDC73, DDB1, HNRNPH3 | MEN1 3817/4885KMT2A 3437/4885MAPT 3840/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.