Known targets — ChEMBL curated mechanism
CHRM1CHRM2CHRM3CHRM4CHRM5SLC6A2dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of None. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 6/20 | 0.63 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.63 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.63 |
| ▸ | GFER | P55789 | 3/20 | 0.63 |
| ▸ | MAPT | P10636 | 3/20 | 0.63 |
| ▸ | LMNA | P02545 | 2/20 | 0.63 |
| ▸ | ALPG | P10696 | 1/20 | 0.63 |
| ▸ | THRB | P10828 | 1/20 | 0.63 |
| ▸ | HTT | P42858 | 1/20 | 0.63 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.63 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.63 |
| ▸ | RAB9A | P51151 | 3/20 | 0.53 |
| ▸ | GAA | P10253 | 2/20 | 0.53 |
| ▸ | APOBEC3A | P31941 | 2/20 | 0.53 |
| ▸ | APOBEC3G | Q9HC16 | 2/20 | 0.53 |
| ▸ | NPC1 | O15118 | 2/20 | 0.53 |
| ▸ | CASP1 | P29466 | 1/20 | 0.51 |
| ▸ | BRCA1 | P38398 | 1/20 | 0.51 |
| ▸ | CASP7 | P55210 | 1/20 | 0.51 |
| ▸ | HBB | P68871 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL531127 | 1.00 | MEN1 (0.63) | MEN1KMT2AALDH1A1GFERMAPT | |
| SCHEMBL5402822 | 0.88 | MEN1 (0.61) | MEN1KMT2AALDH1A1GFERMAPT | |
| SCHEMBL6318506 | 0.86 | MEN1 (0.47) | MEN1KMT2AALDH1A1GFERMAPT | |
| SCHEMBL8740701 | 0.85 | MEN1 (0.56) | MEN1KMT2AALDH1A1GFERMAPT | |
| SCHEMBL11398927 | 0.85 | CYP2A6 (0.47) | MEN1KMT2AALDH1A1GFERMAPT | |
| SCHEMBL7044936 | 0.85 | CYP2A6 (0.47) | MEN1KMT2AALDH1A1GFERMAPT | |
| SCHEMBL4688796 | 0.83 | TERT (0.43) | MEN1KMT2AALDH1A1GFERMAPT | |
| SCHEMBL1402879 | 0.83 | MEN1 (0.58) | MEN1KMT2AALDH1A1GFERMAPT | |
| SCHEMBL372527 | 0.83 | CHAT (0.61) | MEN1KMT2AALDH1A1MAPTALPG | |
| SCHEMBL8991523 | 0.82 | MEN1 (0.69) | MEN1KMT2AALDH1A1GFERMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 77 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8861921-B2 | Photovoltaic device with frequency conversion region | WAKE FOREST UNIVERSITY (US) | 2014-10-14 | — | — | US | claimed |
| US-20120134618-A1 | PHOTOVOLTAIC DEVICE WITH FREQUENCY CONVERSION REGION | WAKE FOREST UNIVERSITY | 2012-05-31 | — | — | US | claimed |
| US-7854505-B2 | Passive and active photonic crystal structures and devices | THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS (US) | 2010-12-21 | — | — | US | claimed |
| WO-2010144438-A1 | PHOTOVOLTAIC DEVICE WITH FREQUENCY CONVERSION REGION | WAKE FOREST UNIVERSITY (US) | 2010-12-16 | — | — | WO | claimed |
| US-20090323014-A1 | PASSIVE AND ACTIVE PHOTONIC CRYSTAL STRUCTURES AND DEVICES | THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS (US) | 2009-12-31 | — | — | US | claimed |
| US-20080128618-A1 | Dendrimer Based Electro-Optic Sensor | APPLIED RESEARCH AND PHOTONICS, INC. | 2008-06-05 | — | — | US | claimed |
| US-20080099698-A1 | Dendrimer Based Terahertz Generator | APPLIED RESEARCH AND PHOTONICS, INC. | 2008-05-01 | — | — | US | claimed |
| EP-1200051-B1 | AGENT FOR DYING KERATIN FIBERS | HENKEL KGAA (DE) | 2006-02-01 | — | — | EP | claimed |
| US-20210098528-A1 | Thermoelectric Apparatus And Applications Thereof | UNIV WAKE FOREST (US) | 2021-04-01 | — | — | US | disclosed |
| US-10868077-B2 | Thermoelectric apparatus and applications thereof | WAKE FOREST UNIVERSITY (US) | 2020-12-15 | — | — | US | disclosed |
| US-10840426-B2 | Thermoelectric apparatus and articles and applications thereof | WAKE FOREST UNIVERSITY (US) | 2020-11-17 | — | — | US | disclosed |
| EP-2443683-B1 | WRAPPED OPTOELECTRONIC DEVICES AND METHODS FOR MAKING SAME | UNIV HOUSTON (US) | 2020-02-26 | — | — | EP | disclosed |
| EP-3226316-A1 | THERMOELECTRIC APPARATUS AND ARTICLES AND APPLICATIONS THEREOF | Wake Forest University (US) | 2017-10-04 | — | — | EP | disclosed |
| US-9702870-B2 | Fluorescent dyes and related methods | UNIVERSITY OF WASHINGTON THROUGH ITS CENTER FOR COMMERCIALIZATION (US) | 2017-07-11 | — | — | US | disclosed |
| US-20080002329-A1 | High Dielectric, Non-Linear Capacitor | POHM ARTHUR V | 2008-01-03 | — | — | US | disclosed |
| WO-2007130025-A1 | ORGANIC OPTOELECTRONIC DEVICES AND APPLICATIONS THEREOF | WAKE FOREST UNIVERSITY (US) | 2007-11-15 | — | — | WO | disclosed |
| US-20070206342-A1 | High Dielectric, Non-Linear Nano-Capacitor | NANO-ELECTROCHEM, INC. | 2007-09-06 | — | — | US | disclosed |
| US-20060291278-A1 | Nano-Reflectors for Thin, Flat Display Devices | NANO-ELECTROCHEM, INC. (US) | 2006-12-28 | — | — | US | disclosed |
| US-20030096502-A1 | Method for levelling depressed surface of organic crystals | NATIONAL INSTITUTE OF ADVANCED INDUSTRIAL SCIENCE (JP) | 2003-05-22 | — | — | US | disclosed |
| EP-1312443-A2 | Method of levelling depressed surfaces of organic crystals | National Institute of Advanced Industrial Science and Technology (JP) | 2003-05-21 | — | — | EP | disclosed |