Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 3/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | NPC1 | O15118 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | STAT3 | P40763 | 1/20 | 0.43 |
| ▸ | ATM | Q13315 | 1/20 | 0.43 |
| ▸ | HTR2A | P28223 | 1/20 | 0.40 |
| ▸ | CDK2 | P24941 | 2/20 | 0.40 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.40 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.40 |
| ▸ | CCNT1 | O60563 | 1/20 | 0.40 |
| ▸ | CCNK | O75909 | 1/20 | 0.40 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.40 |
| ▸ | CDK7 | P50613 | 1/20 | 0.40 |
| ▸ | CDK9 | P50750 | 1/20 | 0.40 |
| ▸ | CCNH | P51946 | 1/20 | 0.40 |
| ▸ | MNAT1 | P51948 | 1/20 | 0.40 |
| ▸ | CDK12 | Q9NYV4 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | CASP3 | P42574 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11502287 | 0.76 | RAB9A (0.50) | RAB9AMAPTNPC1SMN1; SMN2STAT3 | |
| SCHEMBL10876379 | 0.75 | MAPT (0.46) | RAB9AMAPTNPC1SMN1; SMN2STAT3 | |
| SCHEMBL171553 | 0.75 | PRMT5 (0.41) | CHRM2CHRM3 | |
| SCHEMBL13490652 | 0.74 | CHRM2 (0.45) | CDK2CHRM2CHRM3CHEK1CCNA2 | |
| SCHEMBL10355472 | 0.74 | RAB9A (0.44) | RAB9AMAPTNPC1SMN1; SMN2STAT3 | |
| SCHEMBL10355473 | 0.74 | RAB9A (0.44) | RAB9AMAPTNPC1SMN1; SMN2STAT3 | |
| SCHEMBL10463415 | 0.73 | RAB9A (0.44) | RAB9AMAPTNPC1SMN1; SMN2STAT3 | |
| SCHEMBL10463412 | 0.73 | RAB9A (0.44) | RAB9AMAPTNPC1SMN1; SMN2STAT3 | |
| SCHEMBL10463413 | 0.73 | RAB9A (0.44) | RAB9AMAPTNPC1SMN1; SMN2STAT3 | |
| SCHEMBL10717317 | 0.73 | RAB9A (0.44) | RAB9AMAPTNPC1SMN1; SMN2STAT3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2426120-A1 | Pyridyltetrahydropyridines and pyridylpiperidines, and method of manufacturing them | Fujifilm Finechemicals Co., Ltd. (JP) | 2012-03-07 | — | — | EP | disclosed |