Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.37 |
| ▸ | LPAR1 | Q92633 | 1/20 | 0.36 |
| ▸ | LPAR5 | Q9H1C0 | 1/20 | 0.36 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.36 |
| ▸ | MRGPRX4 | Q96LA9 | 6/20 | 0.35 |
| ▸ | TRPM8 | Q7Z2W7 | 2/20 | 0.35 |
| ▸ | CD274 | Q9NZQ7 | 2/20 | 0.35 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.35 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.35 |
| ▸ | LTC4S | Q16873 | 1/20 | 0.34 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.34 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.34 |
| ▸ | SCN3A | Q9NY46 | 1/20 | 0.34 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1716217 | 0.92 | NR1H4 (0.37) | NR1H4LPAR1LPAR5PTGDR2MRGPRX4 | |
| SCHEMBL1263801 | 0.85 | NR1H4 (0.38) | NR1H4MRGPRX4CD274FOLH1HTT | |
| SCHEMBL1262609 | 0.81 | HIF1A (0.36) | NR1H4LPAR1LPAR5PTGDR2TRPM8 | |
| SCHEMBL1262605 | 0.80 | HIF1A (0.35) | NR1H4PTGDR2TRPM8LTC4SKCNH2 | |
| SCHEMBL1262607 | 0.80 | HIF1A (0.35) | NR1H4PTGDR2TRPM8LTC4SKCNH2 | |
| SCHEMBL1262610 | 0.80 | HIF1A (0.35) | NR1H4PTGDR2TRPM8LTC4SKCNH2 | |
| SCHEMBL1715706 | 0.80 | BRD4 (0.39) | PTGDR2MRGPRX4CD274PDCD1FOLH1 | |
| SCHEMBL1263381 | 0.78 | MRGPRX4 (0.42) | PTGDR2MRGPRX4CD274FOLH1HTT | |
| SCHEMBL1263400 | 0.77 | NR1H4 (0.38) | NR1H4MRGPRX4CD274FOLH1HTT | |
| SCHEMBL1716016 | 0.74 | MRGPRX4 (0.48) | MRGPRX4ADAM17 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1784173-B1 | PHARMACEUTICAL COMPOSITION FOR PREVENTING AND TREATING METABOLIC BONE DISEASES CONTAINING ALPHA-ARYLMETHOXYACRYLATE DERIVATIVES | KOREA RES INST CHEM TECH (KR) | 2012-01-18 | — | — | EP | claimed |