Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 1/20 | 0.39 |
| ▸ | FFAR1 | O14842 | 9/20 | 0.38 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.38 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.36 |
| ▸ | ACHE | P22303 | 1/20 | 0.36 |
| ▸ | BACE1 | P56817 | 1/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.36 |
| ▸ | SCN3A | Q9NY46 | 1/20 | 0.36 |
| ▸ | CD274 | Q9NZQ7 | 2/20 | 0.36 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.36 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.36 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.35 |
| ▸ | ALDH2 | P05091 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1715708 | 0.93 | ACHE (0.39) | BRD4FFAR1FOLH1PTGDR2ACHE | |
| SCHEMBL1716768 | 0.86 | FFAR1 (0.40) | BRD4FFAR1FOLH1PTGDR2ACHE | |
| SCHEMBL1263376 | 0.84 | FFAR1 (0.40) | FFAR1FOLH1CD274MRGPRX4 | |
| SCHEMBL1716766 | 0.84 | FFAR1 (0.40) | BRD4FFAR1FOLH1PTGDR2ACHE | |
| SCHEMBL1716767 | 0.84 | FFAR1 (0.40) | BRD4FFAR1FOLH1PTGDR2ACHE | |
| SCHEMBL1263796 | 0.82 | FFAR1 (0.41) | BRD4FFAR1KCNH2SCN3AALDH2 | |
| SCHEMBL1263798 | 0.80 | FFAR1 (0.40) | BRD4FFAR1KCNH2SCN3AALDH2 | |
| SCHEMBL1263792 | 0.80 | FFAR1 (0.40) | BRD4FFAR1KCNH2SCN3AALDH2 | |
| SCHEMBL1263790 | 0.80 | FFAR1 (0.40) | BRD4FFAR1KCNH2SCN3AALDH2 | |
| SCHEMBL1716216 | 0.80 | NR1H4 (0.37) | FOLH1PTGDR2KCNH2SCN3ACD274 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1784173-B1 | PHARMACEUTICAL COMPOSITION FOR PREVENTING AND TREATING METABOLIC BONE DISEASES CONTAINING ALPHA-ARYLMETHOXYACRYLATE DERIVATIVES | KOREA RES INST CHEM TECH (KR) | 2012-01-18 | — | — | EP | claimed |