Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 5/20 | 0.49 |
| ▸ | MEN1 | O00255 | 4/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | HTR2A | P28223 | 1/20 | 0.46 |
| ▸ | HTR1A | P08908 | 1/20 | 0.44 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.44 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | CA12 | O43570 | 1/20 | 0.43 |
| ▸ | CA1 | P00915 | 1/20 | 0.43 |
| ▸ | CA2 | P00918 | 1/20 | 0.43 |
| ▸ | CA4 | P22748 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17177095 | 1.00 | KCNH2 (0.49) | KCNH2MEN1KMT2AALDH1A1TSHR | |
| SCHEMBL19245593 | 0.92 | CA12 (0.47) | KCNH2MEN1KMT2AALDH1A1TSHR | |
| SCHEMBL19212464 | 0.92 | CA12 (0.47) | KCNH2MEN1KMT2AALDH1A1TSHR | |
| SCHEMBL6621881 | 0.92 | CA12 (0.47) | KCNH2MEN1KMT2AALDH1A1TSHR | |
| SCHEMBL19245780 | 0.92 | CA12 (0.47) | KCNH2MEN1KMT2AALDH1A1TSHR | |
| SCHEMBL16609244 | 0.90 | TSHR (0.47) | KCNH2MEN1KMT2AALDH1A1TSHR | |
| SCHEMBL17164079 | 0.88 | CDC25C (0.43) | KCNH2MEN1KMT2AALDH1A1TSHR | |
| SCHEMBL6618592 | 0.86 | MEN1 (0.48) | KCNH2MEN1KMT2AALDH1A1TSHR | |
| SCHEMBL6618598 | 0.86 | MEN1 (0.48) | KCNH2MEN1KMT2AALDH1A1TSHR | |
| SCHEMBL31362021 | 0.85 | MEN1 (0.46) | KCNH2MEN1KMT2AALDH1A1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015155664-A1 | AN IMPROVED PROCESS FOR THE PREPARATION OF 2-(2-AMINOTHIAZOL-4-YL)-N-[4-(2-[[(2R)-2-HYDROXY-2- PHENYLETHYL]AMINO]-ETHYL)PHENYL]ACETAMIDE | SUVEN LIFE SCIENCES LIMITED (IN) | 2015-10-15 | — | — | WO | disclosed |