Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 1/20 | 0.47 |
| ▸ | CA1 | P00915 | 1/20 | 0.47 |
| ▸ | CA2 | P00918 | 1/20 | 0.47 |
| ▸ | CA4 | P22748 | 1/20 | 0.47 |
| ▸ | CRHBP | P24387 | 2/20 | 0.47 |
| ▸ | CRHR2 | Q13324 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.46 |
| ▸ | HTR2A | P28223 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 3/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | MC4R | P32245 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19245593 | 1.00 | CA12 (0.47) | CA12CA1CA2CA4CRHBP | |
| SCHEMBL6621881 | 1.00 | CA12 (0.47) | CA12CA1CA2CA4CRHBP | |
| SCHEMBL17164147 | 0.92 | KCNH2 (0.49) | CA12CA1CA2CA4ALDH1A1 | |
| SCHEMBL17177095 | 0.92 | KCNH2 (0.49) | CA12CA1CA2CA4ALDH1A1 | |
| SCHEMBL19245780 | 0.90 | CA12 (0.47) | CA12CA1CA2CA4CRHBP | |
| SCHEMBL8671546 | 0.88 | KCNH2 (0.51) | ALDH1A1LMNAKCNH2MEN1KMT2A | |
| SCHEMBL28373072 | 0.86 | ALDH1A1 (0.60) | CRHBPCRHR2ALDH1A1LMNAHTR2A | |
| SCHEMBL16796535 | 0.86 | ALDH1A1 (0.60) | CRHBPCRHR2ALDH1A1LMNAHTR2A | |
| SCHEMBL10346971 | 0.86 | MC4R (0.43) | CRHBPCRHR2ALDH1A1LMNAKCNH2 | |
| SCHEMBL16609244 | 0.86 | TSHR (0.47) | CA12CA1CA2CA4ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017137784-A1 | METHOD FOR THE PRODUCTION OF MORPHOLOGICALLY HOMOGENOUS MIRABEGRON AND MIRABEGRON MONOHYDROCHLORIDE | EGIS GYÓGYSZERGYÁR ZRT. (HU) | 2017-08-17 | — | — | WO | claimed |
| WO-2017137784-A1 | METHOD FOR THE PRODUCTION OF MORPHOLOGICALLY HOMOGENOUS MIRABEGRON AND MIRABEGRON MONOHYDROCHLORIDE | EGIS GYÓGYSZERGYÁR ZRT. (HU) | 2017-08-17 | — | — | WO | disclosed |
| WO-2017137784-A1 | METHOD FOR THE PRODUCTION OF MORPHOLOGICALLY HOMOGENOUS MIRABEGRON AND MIRABEGRON MONOHYDROCHLORIDE | EGIS GYÓGYSZERGYÁR ZRT. (HU) | 2017-08-17 | — | — | WO | disclosed |
| CN-104016877-B | Acetylaniline compounds and application thereof in preparation of mirabegron | 南京海融制药有限公司 | 2017-02-15 | — | — | CN | disclosed |