Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ROCK2 | O75116 | 20/20 | 1.00 |
| ▸ | ROCK1 | Q13464 | 13/20 | 1.00 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17040775 | 1.00 | ROCK2 (1.00) | ROCK2ROCK1 | |
| Hydrochloric Acid SCHEMBL29575984 | 0.99 | ROCK2 (0.98) | ROCK2ROCK1 | |
| Hydrochloric Acid SCHEMBL17025865 | 0.99 | ROCK2 (0.98) | ROCK2ROCK1 | |
| SCHEMBL17038100 | 0.92 | ROCK2 (1.00) | ROCK2ROCK1 | |
| SCHEMBL17041184 | 0.91 | ROCK2 (1.00) | ROCK2ROCK1 | |
| SCHEMBL1724078 | 0.84 | ROCK2 (0.72) | ROCK2ROCK1 | |
| SCHEMBL1724986 | 0.84 | ROCK2 (0.72) | ROCK2ROCK1 | |
| SCHEMBL1724076 | 0.84 | ROCK2 (0.72) | ROCK2ROCK1 | |
| SCHEMBL15639833 | 0.84 | ROCK2 (0.85) | ROCK2ROCK1 | |
| SCHEMBL32670211 | 0.84 | ROCK2 (0.85) | ROCK2ROCK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2903618-B1 | RHO KINASE INHIBITORS | KADMON CORP LLC (US) | 2022-06-01 | — | — | EP | disclosed |
| CN-113773308-A | RHO kinase inhibitors | 卡德门企业有限公司 | 2021-12-10 | — | — | CN | disclosed |
| CN-113637008-A | RHO kinase inhibitors | 卡德门企业有限公司 | 2021-11-12 | — | — | CN | disclosed |
| CN-113637007-A | RHO kinase inhibitors | 卡德门企业有限公司 | 2021-11-12 | — | — | CN | disclosed |
| CN-113620933-A | RHO kinase inhibitors | 卡德门企业有限公司 | 2021-11-09 | — | — | CN | disclosed |
| WO-2015157556-A1 | TREATMENT OF GVHD | KADMON CORPORATION, LLC (US) | 2015-10-15 | — | — | WO | disclosed |