SCHEMBL17164641

SCHEMBL17164641

COc1ccc(CC=O)c(C)n1

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NNMT P40261 1/20 0.45
POLB P06746 1/20 0.35
TDP1 Q9NUW8 1/20 0.35
MTNR1A P48039 8/20 0.35
MTNR1B P49286 8/20 0.35
PDE10A Q9Y233 6/20 0.35
CYP1A2 P05177 1/20 0.34
KMT2A Q03164 1/20 0.34
BRD9 Q9H8M2 1/20 0.33
BRD7 Q9NPI1 1/20 0.33
PDE2A O00408 1/20 0.33
PDE5A O76074 1/20 0.33
PDE4A P27815 1/20 0.33
PDE4D Q08499 1/20 0.33
PDE7A Q13946 1/20 0.33
PDE3A Q14432 1/20 0.33
PDE11A Q9HCR9 1/20 0.33
PDE7B Q9NP56 1/20 0.33
TXNRD1 Q16881 1/20 0.33
DDAH1 O94760 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16111693 0.82 POLB (0.46) NNMTPOLBTDP1KMT2ABRD9
SCHEMBL9016286 0.81 NNMT (0.50) NNMTPOLBTDP1MTNR1AMTNR1B
Formic Acid SCHEMBL29276423 0.78 NNMT (0.45) NNMTPOLBTDP1MTNR1AMTNR1B
SCHEMBL21591627 0.78
SCHEMBL14032510 0.76 NNMT (0.44) NNMTPOLBTDP1MTNR1AMTNR1B
SCHEMBL25624100 0.76 NNMT (0.44) NNMTPOLBTDP1MTNR1AMTNR1B
SCHEMBL1904976 0.76 NNMT (0.49) NNMTPOLBTDP1MTNR1AMTNR1B
SCHEMBL14032509 0.76 NNMT (0.49) NNMTPOLBTDP1MTNR1AMTNR1B
SCHEMBL1923109 0.74 NNMT (0.51) NNMTPOLBTDP1MTNR1AMTNR1B
SCHEMBL14032801 0.73 NNMT (0.50) NNMTPOLBTDP1PDE10ACYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2015157005-A1 SUBSTITUTED TOLYL FUNGICIDE MIXTURES E I DU PONT DE NEMOURS AND COMPANY (US) 2015-10-15 WO disclosed