Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.70 |
| ▸ | RAB9A | P51151 | 2/20 | 0.67 |
| ▸ | GFER | P55789 | 2/20 | 0.67 |
| ▸ | NPC1 | O15118 | 1/20 | 0.67 |
| ▸ | MEN1 | O00255 | 5/20 | 0.65 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.65 |
| ▸ | ESR1 | P03372 | 2/20 | 0.59 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.59 |
| ▸ | CA12 | O43570 | 3/20 | 0.58 |
| ▸ | CA7 | P43166 | 2/20 | 0.58 |
| ▸ | CA4 | P22748 | 1/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.57 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.57 |
| ▸ | SIRT6 | Q8N6T7 | 1/20 | 0.56 |
| ▸ | CA1 | P00915 | 1/20 | 0.56 |
| ▸ | CA2 | P00918 | 1/20 | 0.56 |
| ▸ | CA9 | Q16790 | 1/20 | 0.56 |
| ▸ | GAA | P10253 | 2/20 | 0.55 |
| ▸ | MAPT | P10636 | 1/20 | 0.55 |
| ▸ | PKM | P14618 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17166043 | 0.95 | POLB (0.65) | POLBRAB9AGFERNPC1MEN1 | |
| SCHEMBL15614028 | 0.89 | POLB (0.69) | POLBRAB9AGFERMEN1KMT2A | |
| SCHEMBL15176761 | 0.88 | RAB9A (0.65) | POLBRAB9AGFERNPC1MEN1 | |
| SCHEMBL9564278 | 0.86 | RAB9A (0.57) | POLBRAB9AGFERNPC1MEN1 | |
| SCHEMBL9564251 | 0.86 | MEN1 (0.64) | POLBRAB9AGFERNPC1MEN1 | |
| SCHEMBL17166274 | 0.86 | RAB9A (0.76) | POLBRAB9AGFERNPC1MEN1 | |
| SCHEMBL23480000 | 0.84 | RAB9A (0.82) | POLBRAB9AGFERMEN1KMT2A | |
| SCHEMBL10189785 | 0.84 | MEN1 (0.79) | POLBRAB9AGFERMEN1KMT2A | |
| SCHEMBL14338938 | 0.83 | RAB9A (0.73) | POLBRAB9AGFERMEN1KMT2A | |
| SCHEMBL15614027 | 0.82 | MEN1 (0.70) | POLBRAB9AGFERMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9155792-B2 | RecA inhibitors with antibiotic activity, compositions and methods of use | TRUSTEES OF BOSTON UNIVERSITY (US) | 2015-10-13 | — | — | US | disclosed |