Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCRTR1 | O43613 | 16/20 | 0.41 |
| ▸ | HCRTR2 | O43614 | 3/20 | 0.39 |
| ▸ | LATS1 | O95835 | 3/20 | 0.38 |
| ▸ | LATS2 | Q9NRM7 | 3/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18607821 | 0.86 | HCRTR1 (0.41) | HCRTR1HCRTR2 | |
| SCHEMBL17021488 | 0.86 | HCRTR1 (0.41) | HCRTR1HCRTR2 | |
| SCHEMBL22877019 | 0.85 | HCRTR1 (0.54) | HCRTR1HCRTR2LATS1LATS2 | |
| Hydrochloric Acid SCHEMBL17028121 | 0.83 | HCRTR1 (0.39) | HCRTR1HCRTR2 | |
| Hydrochloric Acid SCHEMBL17007149 | 0.83 | HCRTR1 (0.39) | HCRTR1HCRTR2 | |
| Hydrochloric Acid SCHEMBL17007150 | 0.83 | HCRTR1 (0.39) | HCRTR1HCRTR2 | |
| SCHEMBL17166533 | 0.75 | HCRTR1 (0.54) | HCRTR1HCRTR2 | |
| SCHEMBL17017337 | 0.71 | HCRTR1 (0.53) | HCRTR1HCRTR2 | |
| SCHEMBL18607822 | 0.69 | HCRTR1 (0.53) | HCRTR1HCRTR2 | |
| SCHEMBL17007200 | 0.69 | HCRTR1 (0.81) | HCRTR1HCRTR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9156829-B2 | Cycloalkyl and heterocycloalkyl compounds as orexin receptor antagonists | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2015-10-13 | — | — | US | disclosed |