Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIM1 | P11309 | 1/20 | 0.39 |
| ▸ | AKT2 | P31751 | 1/20 | 0.39 |
| ▸ | KDR | P35968 | 5/20 | 0.33 |
| ▸ | EGFR | P00533 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1454418 | 0.95 | PIM1 (0.39) | PIM1AKT2KDREGFR | |
| SCHEMBL1717121 | 0.91 | PIM1 (0.37) | PIM1AKT2KDR | |
| SCHEMBL1455351 | 0.90 | PIM1 (0.37) | PIM1AKT2KDR | |
| SCHEMBL1455350 | 0.89 | PIM1 (0.39) | PIM1AKT2KDR | |
| SCHEMBL1454998 | 0.88 | PIM1 (0.38) | PIM1AKT2KDR | |
| SCHEMBL1454273 | 0.86 | PIM1 (0.38) | PIM1AKT2 | |
| SCHEMBL1455126 | 0.86 | HPGDS (0.35) | PIM1AKT2KDR | |
| SCHEMBL1455257 | 0.86 | PIM1 (0.36) | PIM1AKT2 | |
| SCHEMBL1455069 | 0.86 | PIM1 (0.41) | PIM1AKT2KDREGFR | |
| SCHEMBL1455352 | 0.86 | PIM1 (0.37) | PIM1AKT2KDREGFR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1979348-B1 | ANTI-VIRAL COMPOUNDS | ABBOTT LAB (US) | 2012-01-18 | — | — | EP | disclosed |
| EP-1979348-A2 | ANTI-VIRAL COMPOUNDS | Abbott Laboratories (US) | 2008-10-15 | — | — | EP | disclosed |
| WO-2007076034-A2 | ANTI-VIRAL COMPOUNDS | ABBOTT LABORATORIES (US) | 2007-07-05 | — | — | WO | disclosed |