Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | HDAC3 | O15379 | 3/20 | 0.35 |
| ▸ | HDAC4 | P56524 | 3/20 | 0.35 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.35 |
| ▸ | HDAC7 | Q8WUI4 | 3/20 | 0.35 |
| ▸ | HDAC2 | Q92769 | 3/20 | 0.35 |
| ▸ | HDAC10 | Q969S8 | 3/20 | 0.35 |
| ▸ | HDAC11 | Q96DB2 | 3/20 | 0.35 |
| ▸ | HDAC8 | Q9BY41 | 3/20 | 0.35 |
| ▸ | HDAC6 | Q9UBN7 | 3/20 | 0.35 |
| ▸ | HDAC9 | Q9UKV0 | 3/20 | 0.35 |
| ▸ | HDAC5 | Q9UQL6 | 3/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | ACHE | P22303 | 2/20 | 0.33 |
| ▸ | NAMPT | P43490 | 3/20 | 0.33 |
| ▸ | BCHE | P06276 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15773182 | 0.99 | SMN1; SMN2 (0.44) | SMN1; SMN2HPGDHTTALDH1A1HDAC3 | |
| SCHEMBL17168610 | 0.95 | SMN1; SMN2 (0.44) | SMN1; SMN2HPGDHTTALDH1A1HDAC3 | |
| SCHEMBL17168856 | 0.95 | SMN1; SMN2 (0.45) | SMN1; SMN2HPGDHTTALDH1A1HDAC3 | |
| SCHEMBL17168462 | 0.94 | SMN1; SMN2 (0.46) | SMN1; SMN2HPGDHTTALDH1A1HDAC3 | |
| SCHEMBL17167517 | 0.94 | SMN1; SMN2 (0.41) | SMN1; SMN2HPGDHTTALDH1A1HDAC3 | |
| SCHEMBL15773145 | 0.93 | SMN1; SMN2 (0.43) | SMN1; SMN2HPGDHTTHDAC3HDAC4 | |
| SCHEMBL19646412 | 0.91 | SMN1; SMN2 (0.48) | SMN1; SMN2HPGDHTTALDH1A1HDAC3 | |
| SCHEMBL17168743 | 0.91 | SMN1; SMN2 (0.50) | SMN1; SMN2HPGDHTTALDH1A1HDAC3 | |
| SCHEMBL20999873 | 0.91 | SMN1; SMN2 (0.50) | SMN1; SMN2HPGDHTTALDH1A1HDAC3 | |
| SCHEMBL26382038 | 0.91 | SMN1; SMN2 (0.50) | SMN1; SMN2HPGDHTTALDH1A1HDAC3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9828341-B2 | Dendritic core compounds | VICTORIA LINK LIMITED (NZ) | 2017-11-28 | — | — | US | disclosed |
| US-20150291522-A1 | DENDRITIC CORE COMPOUNDS | CALLAGHAN INNOVATION RESEARCH LIMITED (NZ) | 2015-10-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150291522-A1 | DENDRITIC CORE COMPOUNDS | FLOT1, DBN1, DCTN3 | SMN1; SMN2 4501/4885HPGD 1910/4885HTT 2797/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.