FLOT1 — patent landscape

Top predicted compounds (top 20 by supporting neighbours, then confidence)

Compound	Confidence	Supporting neighbours
Molibresib (SCHEMBL1872390)	1.00	1/20
Molibresib (SCHEMBL12671490)	1.00	1/20
Molibresib (SCHEMBL12966358)	1.00	1/20
SCHEMBL9998851	0.91	1/20
SCHEMBL14756282	0.88	1/20
SCHEMBL15980874	0.88	1/20
SCHEMBL12966165	0.87	1/20
SCHEMBL14756215	0.87	1/20
SCHEMBL14756339	0.87	1/20
SCHEMBL15980861	0.87	1/20
SCHEMBL9998825	0.86	1/20
SCHEMBL15980893	0.86	1/20
SCHEMBL15980803	0.86	1/20
SCHEMBL1874116	0.85	1/20
SCHEMBL12671221	0.85	1/20
SCHEMBL14756021	0.85	1/20
SCHEMBL14756240	0.85	1/20
SCHEMBL14756287	0.85	1/20
SCHEMBL14756335	0.85	1/20
SCHEMBL14756409	0.85	1/20

Clinical trials — most relevant to FLOT1 by text similarity (a relevance ranking, not an exhaustive list)

Trial	Phase	Status
Fixed-dose vs. Phenotype-based PrAsugrel Dose to MATCH Therapeutic Zone in Asians With Acute Coronary Syndrome	PHASE4	COMPLETED
Lovaza's Effect on the Activation of Platelets	PHASE2	COMPLETED
Melpida: Recombinant Adeno-associated Virus (serotype 9) Encoding a Codon Optimized Human AP4M1 Transgene (hAP4M1opt)	PHASE1/PHASE2	RECRUITING
Treatment of Ectopic Calcification in Fahr's Disease or Syndrome	PHASE2	RECRUITING
Safety, Tolerability, Efficacy and Pharmacodynamics of CAL02 in Severe Pneumonia Caused by Streptococcus Pneumoniae	PHASE1	COMPLETED
Dynamics of Muscle Mitochondria in Type 2 Diabetes (DYNAMMO T2D)	EARLY_PHASE1	COMPLETED
RAFTLIN-1 Levels in Axial Spondyloarthritis and Psoriatic Arthritis	nan	COMPLETED
Studying the Role of Circulating Tumor Cell Clusters in Patients With High-risk Early Breast Cancer, Study GALIA	nan	RECRUITING
Characterization of the Platelet Inflammatory Response in NAFL and NASH	nan	UNKNOWN
Immune Cell Response to Stimuli	nan	RECRUITING
Capacitation-associated Protein Tyrosine Phosphorylation As a Possible Biomarker of Sperm Selection	nan	COMPLETED
Characterization of New Candidate Genes in Cases of Human Inherited Thrombocytopenia (CATCH)	nan	COMPLETED
Role of USP35 in the Detection of Ferroptosis in Juvenile Autoimmune Hepatitis	nan	NOT_YET_RECRUITING
Natural History Study of SLC25A46 Mutation-related Mitochondriopathy	nan	COMPLETED
Statin Therapy and COVID-19 Infection	nan	COMPLETED
Dynamics of Muscle Mitochondria in Type 2 Diabetes Exercise	nan	COMPLETED
A Study of Circulating Exosome Proteomics In Gallbladder Carcinoma Patients	nan	UNKNOWN
Biomarker for Mucolipidosis Disorder Type I, II, III, IV (BioML)	nan	WITHDRAWN
5-Aminolevulinic Acid (5-ALA) to Enhance Visualization of Malignant Tumor	nan	COMPLETED
Antiplatelet and Anti-inflammatory Effects of Statins and Ezetimibe	nan	COMPLETED
Genetic Variation in CLTCL1 and Whole-body Glucose Control	nan	COMPLETED
Significance of Immunohistochemical Expression of Fascin-1 in Colorectal Carcinoma	nan	COMPLETED
Early Recognition and Intervention in Siblings at High-risk for Neurodevelopmental Disorder	nan	UNKNOWN
Multicentric Prospective Study of Genetic and Physiopathology Concerning Dysregulation of Complement During Repeated Fetal Abortions	nan	COMPLETED
The Gut-Skin Axis Integrity in Psoriatic Patients	nan	UNKNOWN
FGL2/Fibroleukin and Hepatitis C Virus Recurrence Post Liver Transplantation	nan	UNKNOWN
Cell Free Circulating Nucleic Acids as New Tumor Diagnostics From Human Plasma Samples.	nan	UNKNOWN
Expression Pattern and Possible Clinical Significance of CD81 In Myeloid Leukemia	nan	NOT_YET_RECRUITING
Genetics of Endocrine Tumours - Familial Isolated Pituitary Adenoma - FIPA	nan	RECRUITING
High Dose Omega-3 Fatty Acids in the Treatment of Sport Related Concussions	nan	COMPLETED

Related proteins — ESM-2 sequence neighbours (a FLOT1 binder may also engage these)

Protein	Name	Similarity
Q08DN8	—	1.000	Q08DN8 →
O08917	—	1.000	O08917 →
Q767L6	—	1.000	Q767L6 →
Q9Z1E1	—	1.000	Q9Z1E1 →
Q5TM70	—	1.000	Q5TM70 →
Q7YR41	—	1.000	Q7YR41 →
Q5RBL4	—	1.000	Q5RBL4 →
O61491	—	1.000	O61491 →
A6QLR4	—	1.000	A6QLR4 →
Q98TZ8	—	1.000	Q98TZ8 →
O42305	—	0.999	O42305 →
O13127	—	0.998	O13127 →
Q60634	—	0.996	Q60634 →
Q9Z2S9	—	0.996	Q9Z2S9 →
Q14254	—	0.995	Q14254 →
D2XNR2	—	0.994	D2XNR2 →
O61492	—	0.994	O61492 →
O32076	—	0.993	O32076 →
D2XNR1	—	0.990	D2XNR1 →
Q501E6	—	0.990	Q501E6 →
D2XNQ8	—	0.989	D2XNQ8 →
D2XNQ9	—	0.989	D2XNQ9 →
Q9AV57	—	0.986	Q9AV57 →
P72655	—	0.986	P72655 →
D2XNR0	—	0.985	D2XNR0 →
Q9LV90	—	0.984	Q9LV90 →
Q4V3D6	—	0.984	Q4V3D6 →
P0AA53	—	0.982	P0AA53 →
P0AA55	—	0.982	P0AA55 →
Q21190	—	0.981	Q21190 →