SCHEMBL17169588

SCHEMBL17169588

Cc1cccc(C)c1-c1cc(C)c(N2c3ccccc3N(C3CCCCC3)[C@H]2C)c(C)n1

nearest known ligand 0.33

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
HPGD P15428 1/20 0.33
NPC1 O15118 1/20 0.31
MAPT P10636 1/20 0.31
ALOX15 P16050 1/20 0.31
RAB9A P51151 1/20 0.31
C5AR1 P21730 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17169601 0.99 NPC1 (0.32) HPGDNPC1MAPTALOX15RAB9A
SCHEMBL17169599 0.85 ALDH1A1 (0.40) HPGDMAPTALOX15
SCHEMBL17169598 0.84 ALDH1A1 (0.38) HPGDNPC1MAPTALOX15RAB9A
SCHEMBL17169597 0.82 ALDH1A1 (0.32) MAPTC5AR1
SCHEMBL17169635 0.81 HPGD (0.32) HPGDMAPT
SCHEMBL17169627 0.80 MAP4K1 (0.31) HPGD
SCHEMBL17169602 0.77 ALDH1A1 (0.35) ALOX15C5AR1
SCHEMBL17169576 0.77 C5AR1 (0.34) HPGDC5AR1
SCHEMBL17173547 0.77 HPGD (0.36) HPGDNPC1MAPTALOX15RAB9A
SCHEMBL17169577 0.76 MAPT (0.33) HPGDNPC1MAPTALOX15RAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9905785-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2018-02-27 US disclosed
US-9905785-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2018-02-27 US disclosed
US-20150295189-A1 Organic Electroluminescent Materials and Devices UNIVERSAL DISPLAY CORPORATION 2015-10-15 US disclosed