SCHEMBL1716993

SCHEMBL1716993

CC(=O)c1cc[n+](C)c(C(C)=O)c1.Cc1ccc(O)cc1S(=O)(=O)[O-]

nearest known ligand 0.39

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
PTGS1 P23219 1/20 0.39
HSD17B1 P14061 3/20 0.38
GAA P10253 3/20 0.36
ALDH1A1 P00352 3/20 0.36
PKM P14618 1/20 0.36
FFAR4 Q5NUL3 1/20 0.36
PTGER4 P35408 1/20 0.32
TSHR P16473 1/20 0.31
LMNA P02545 2/20 0.30
MAPT P10636 1/20 0.30
RAB9A P51151 1/20 0.30
HTT P42858 1/20 0.30
SMN1; SMN2 Q16637 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24353 0.87 PTGS1 (0.43) PTGS1HSD17B1GAAALDH1A1PKM
SCHEMBL23221 0.84 PTGS1 (0.40) PTGS1HSD17B1GAAALDH1A1PKM
SCHEMBL291072 0.81 PTGS1 (0.40) PTGS1HSD17B1GAAALDH1A1PKM
SCHEMBL1712547 0.81 PTGS1 (0.44) PTGS1HSD17B1GAAALDH1A1PKM
SCHEMBL290802 0.81 PTGS1 (0.39) PTGS1HSD17B1GAAALDH1A1PKM
SCHEMBL290938 0.81 HSD17B1 (0.41) PTGS1HSD17B1GAAALDH1A1PKM
Sulfuric Acid SCHEMBL2184192 0.80 FFAR4 (0.36) GAAALDH1A1FFAR4LMNAMAPT
Sulfuric Acid SCHEMBL1712898 0.80 FFAR4 (0.36) GAAALDH1A1FFAR4LMNAMAPT
SCHEMBL290657 0.79 PTGS1 (0.38) PTGS1HSD17B1GAAALDH1A1PKM
SCHEMBL1716992 0.78 MAPT (0.43) GAAALDH1A1PKMFFAR4LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2320854-B1 BLEACHING AGENT COMPRISING 2-ACYLPYRIDINIUM DERIVATIVES HENKEL AG & CO KGAA (DE) 2012-01-18 EP disclosed