Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 6/20 | 0.50 |
| ▸ | CYP17A1 | P05093 | 2/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.46 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.38 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 2/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | CASP3 | P42574 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.38 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.38 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.38 |
| ▸ | DEGS1 | O15121 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11153024 | 0.95 | CYP19A1 (0.54) | CYP19A1CYP17A1CYP3A4AOC3MAPK1 | |
| SCHEMBL17172233 | 0.85 | CYP19A1 (0.42) | CYP19A1CYP17A1CYP3A4ESR2KMT2A | |
| SCHEMBL17185897 | 0.84 | ABL1 (0.41) | CYP19A1 | |
| SCHEMBL17159520 | 0.84 | ABL1 (0.41) | CYP19A1 | |
| SCHEMBL17171891 | 0.84 | KIF11 (0.48) | CYP19A1CYP3A4 | |
| SCHEMBL17171860 | 0.83 | DRD1 (0.38) | CYP19A1CYP17A1CYP3A4 | |
| SCHEMBL17171863 | 0.83 | ATM (0.47) | CYP19A1CYP17A1CYP3A4 | |
| SCHEMBL17171869 | 0.83 | CYP19A1 (0.59) | CYP19A1CYP17A1CYP3A4KMT2A | |
| SCHEMBL13772981 | 0.82 | CA1 (0.50) | ESR2KMT2AAOC3MAPK1MAPT | |
| SCHEMBL17171861 | 0.81 | CYP19A1 (0.54) | CYP19A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9957252-B2 | Metalloenzyme inhibitor compounds as fungicides | DOW AGROSCIENCES LLC (US) | 2018-05-01 | — | — | US | disclosed |
| US-9957252-B2 | Metalloenzyme inhibitor compounds as fungicides | DOW AGROSCIENCES LLC (US) | 2018-05-01 | — | — | US | disclosed |
| US-20170233369-A1 | METALLOENZYME INHIBITOR COMPOUNDS AS FUNGICIDES | DOW AGROSCIENCES LLC | 2017-08-17 | — | — | US | disclosed |
| US-20170233369-A1 | METALLOENZYME INHIBITOR COMPOUNDS AS FUNGICIDES | DOW AGROSCIENCES LLC | 2017-08-17 | — | — | US | disclosed |
| US-9663491-B2 | Metalloenzyme inhibitor compounds as fungicides | DOW AGROSCIENCES LLC (US) | 2017-05-30 | — | — | US | disclosed |
| US-9663491-B2 | Metalloenzyme inhibitor compounds as fungicides | DOW AGROSCIENCES LLC (US) | 2017-05-30 | — | — | US | disclosed |
| WO-2015160664-A1 | METALLOENZYME INHIBITOR COMPOUNDS AS FUNGICIDES | DOW AGROSCIENCES LLC (US) | 2015-10-22 | — | — | WO | disclosed |
| US-20150291557-A1 | METALLOENZYME INHIBITOR COMPOUNDS AS FUNGICIDES | DOW AGROSCIENCES LLC | 2015-10-15 | — | — | US | disclosed |
| US-20150291557-A1 | METALLOENZYME INHIBITOR COMPOUNDS AS FUNGICIDES | DOW AGROSCIENCES LLC | 2015-10-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150291557-A1 | METALLOENZYME INHIBITOR COMPOUNDS AS FUNGICIDES | GPX1, POR, MGAM | CYP19A1 63/4885CYP17A1 46/4885CYP3A4 89/4885 |
| US-20170233369-A1 | METALLOENZYME INHIBITOR COMPOUNDS AS FUNGICIDES | GPX1, POR, MGAM | CYP19A1 63/4885CYP17A1 46/4885CYP3A4 89/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.