Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.62 |
| ▸ | HPGD | P15428 | 2/20 | 0.60 |
| ▸ | NPSR1 | Q6W5P4 | 4/20 | 0.58 |
| ▸ | MAPT | P10636 | 3/20 | 0.58 |
| ▸ | HTT | P42858 | 3/20 | 0.58 |
| ▸ | LMNA | P02545 | 2/20 | 0.58 |
| ▸ | CNR1 | P21554 | 2/20 | 0.58 |
| ▸ | GPR55 | Q9Y2T6 | 2/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.57 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.57 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.56 |
| ▸ | MEN1 | O00255 | 2/20 | 0.56 |
| ▸ | MCOLN3 | Q8TDD5 | 1/20 | 0.56 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.55 |
| ▸ | KLK7 | P49862 | 1/20 | 0.55 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.55 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.55 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10186895 | 0.87 | HPGD (0.61) | HPGDNPSR1LMNAKMT2AALDH1A1 | |
| SCHEMBL666044 | 0.81 | HPGD (0.70) | HPGDMAPTLMNASMN1; SMN2KMT2A | |
| SCHEMBL2997022 | 0.81 | KMT2A (0.59) | HPGDNPSR1MAPTLMNASMN1; SMN2 | |
| SCHEMBL10300184 | 0.81 | KMT2A (0.59) | KDM4EHPGDNPSR1LMNASMN1; SMN2 | |
| SCHEMBL15756100 | 0.80 | C5AR1 (0.62) | KDM4ENPSR1MAPTHTTLMNA | |
| SCHEMBL13577043 | 0.78 | HPGD (0.50) | HPGDNPSR1MAPTHTTLMNA | |
| SCHEMBL3002789 | 0.78 | VCAM1 (0.60) | HPGDLMNASMN1; SMN2KMT2AALDH1A1 | |
| SCHEMBL11441279 | 0.77 | C5AR1 (0.67) | HPGDNPSR1MAPTHTTLMNA | |
| SCHEMBL17174229 | 0.76 | C5AR1 (0.57) | LMNASMN1; SMN2ALDH1A1MCOLN3PSEN1 | |
| SCHEMBL27180764 | 0.75 | KLK7 (0.72) | KDM4EHPGDMAPTLMNASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20150291517-A1 | BENZENESULFONAMIDE COMPOUNDS FOR SOMATIC EMBRYOGENESIS IN PLANTS | STICHTING DIENST LANDBOUWKUNDIG ONDERZOEK (NL) | 2015-10-15 | — | — | US | disclosed |
| US-20150291517-A1 | BENZENESULFONAMIDE COMPOUNDS FOR SOMATIC EMBRYOGENESIS IN PLANTS | STICHTING DIENST LANDBOUWKUNDIG ONDERZOEK (NL) | 2015-10-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150291517-A1 | BENZENESULFONAMIDE COMPOUNDS FOR SOMATIC EMBRYOGENESIS IN PLANTS | KCNJ2, HCN2, HACL2 | KDM4E 184/4885HPGD 3841/4885NPSR1 2987/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.