Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 16/20 | 0.59 |
| ▸ | DPP7 | Q9UHL4 | 10/20 | 0.59 |
| ▸ | DPP8 | Q6V1X1 | 9/20 | 0.59 |
| ▸ | DPP9 | Q86TI2 | 5/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | FAP | Q12884 | 3/20 | 0.44 |
| ▸ | PREP | P48147 | 2/20 | 0.44 |
| ▸ | PITRM1 | Q5JRX3 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2735521 | 1.00 | DPP4 (0.59) | DPP4DPP7DPP8DPP9MEN1 | |
| SCHEMBL17176288 | 1.00 | DPP4 (0.59) | DPP4DPP7DPP8DPP9MEN1 | |
| SCHEMBL19982003 | 0.90 | DPP4 (0.50) | DPP4DPP7DPP8DPP9MEN1 | |
| SCHEMBL2735526 | 0.90 | DPP4 (0.50) | DPP4DPP7DPP8DPP9MEN1 | |
| SCHEMBL19981943 | 0.89 | ALDH1A1 (0.61) | DPP4DPP7DPP8DPP9MEN1 | |
| SCHEMBL22630456 | 0.89 | ALDH1A1 (0.61) | DPP4DPP7DPP8DPP9MEN1 | |
| SCHEMBL17787623 | 0.89 | ALDH1A1 (0.61) | DPP4DPP7DPP8DPP9MEN1 | |
| SCHEMBL15203536 | 0.85 | DPP4 (0.55) | DPP4DPP7DPP8DPP9MEN1 | |
| SCHEMBL19982022 | 0.84 | DPP4 (0.53) | DPP4DPP7DPP8DPP9FAP | |
| SCHEMBL2735537 | 0.83 | ALDH1A1 (0.54) | DPP4DPP7DPP8DPP9MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015155624-A1 | DIHYDROPYRROLOPYRIMIDINE DERIVATIVES | PFIZER INC. (US) | 2015-10-15 | — | — | WO | disclosed |