SCHEMBL17178366

SCHEMBL17178366

COCCOCCOc1ccc(S)cc1

nearest known ligand 0.53

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 2/20 0.53
RECQL P46063 1/20 0.53
APP P05067 7/20 0.44
MAPK1 P28482 1/20 0.41
TDP1 Q9NUW8 1/20 0.41
L3MBTL1 Q9Y468 1/20 0.40
MAPT P10636 1/20 0.40
CHEK1 O14757 1/20 0.39
RARB P10826 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21564102 1.00 KDM4E (0.53) KDM4ERECQLAPPMAPK1TDP1
SCHEMBL5311543 0.94 KDM4E (0.44) KDM4ERECQLL3MBTL1MAPT
SCHEMBL3611926 0.89 KDM4E (0.61) KDM4ERECQLAPPMAPK1TDP1
SCHEMBL12703538 0.89 KDM4E (0.61) KDM4ERECQLAPPMAPK1TDP1
SCHEMBL17879939 0.83 APP (0.59) KDM4ERECQLAPPMAPT
SCHEMBL12939845 0.83 L3MBTL1 (0.40) KDM4ERECQLMAPK1L3MBTL1MAPT
SCHEMBL22965412 0.83 KDM4E (0.56) KDM4ERECQLAPPMAPK1TDP1
SCHEMBL7042525 0.82 PRSS1 (0.44) KDM4ERECQLMAPK1TDP1L3MBTL1
SCHEMBL8339774 0.82 MAPT (0.52) KDM4ERECQLL3MBTL1MAPT
SCHEMBL24573017 0.82 KDM4E (0.54) KDM4ERECQLAPPTDP1L3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9164384-B2 Patterning process and resist composition SHIN-ETSU CHEMICAL CO., LTD. (JP) 2015-10-20 US disclosed