Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP2 | O75604 | 1/20 | 0.74 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.59 |
| ▸ | GAA | P10253 | 2/20 | 0.59 |
| ▸ | CASP1 | P29466 | 1/20 | 0.59 |
| ▸ | CASP7 | P55210 | 1/20 | 0.59 |
| ▸ | HPGD | P15428 | 6/20 | 0.55 |
| ▸ | TP53 | P04637 | 2/20 | 0.55 |
| ▸ | TSHR | P16473 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 2/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.49 |
| ▸ | LMNA | P02545 | 2/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1718625 | 0.94 | USP2 (0.66) | USP2ALDH1A1GAACASP1CASP7 | |
| SCHEMBL1719303 | 0.88 | ALDH1A1 (0.72) | USP2ALDH1A1GAACASP1CASP7 | |
| SCHEMBL4211812 | 0.88 | USP2 (0.83) | USP2ALDH1A1GAACASP1CASP7 | |
| SCHEMBL1717674 | 0.87 | USP2 (0.82) | USP2ALDH1A1GAACASP1CASP7 | |
| SCHEMBL4210654 | 0.87 | USP2 (0.82) | USP2ALDH1A1GAACASP1CASP7 | |
| SCHEMBL4197430 | 0.85 | USP2 (1.00) | USP2ALDH1A1GAACASP1CASP7 | |
| SCHEMBL1718553 | 0.84 | USP2 (0.75) | USP2ALDH1A1GAACASP1CASP7 | |
| SCHEMBL4204471 | 0.83 | USP2 (0.73) | USP2ALDH1A1GAACASP1CASP7 | |
| SCHEMBL1718008 | 0.81 | USP2 (0.72) | USP2ALDH1A1GAACASP1CASP7 | |
| SCHEMBL4212500 | 0.80 | USP2 (0.71) | USP2ALDH1A1GAACASP1CASP7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1506196-B1 | PYRAZOLOPYRIMIDINES AS SODIUM CHANNEL INHIBITORS | ICAGEN INC (US) | 2012-01-18 | — | — | EP | claimed |
| EP-1506196-B1 | PYRAZOLOPYRIMIDINES AS SODIUM CHANNEL INHIBITORS | ICAGEN INC (US) | 2012-01-18 | — | — | EP | disclosed |