Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.73 |
| ▸ | MEN1 | O00255 | 3/20 | 0.73 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.73 |
| ▸ | RXFP1 | Q9HBX9 | 4/20 | 0.65 |
| ▸ | MAPT | P10636 | 2/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.49 |
| ▸ | TSHR | P16473 | 2/20 | 0.49 |
| ▸ | USP2 | O75604 | 2/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.49 |
| ▸ | HPGD | P15428 | 2/20 | 0.49 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.49 |
| ▸ | CASP1 | P29466 | 2/20 | 0.49 |
| ▸ | CASP7 | P55210 | 2/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.49 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1719053 | 0.99 | KMT2A (0.75) | KMT2AMEN1ALDH1A1RXFP1MAPT | |
| SCHEMBL1719355 | 0.85 | ALDH1A1 (0.98) | KMT2AMEN1ALDH1A1MAPTKDM4E | |
| SCHEMBL1719445 | 0.84 | ALDH1A1 (0.70) | KMT2AMEN1ALDH1A1RXFP1MAPT | |
| SCHEMBL4210744 | 0.84 | ALDH1A1 (1.00) | KMT2AMEN1ALDH1A1MAPTKDM4E | |
| SCHEMBL1720133 | 0.83 | RXFP1 (0.71) | KMT2AMEN1ALDH1A1RXFP1MAPT | |
| SCHEMBL3282802 | 0.82 | RXFP1 (0.69) | KMT2AMEN1ALDH1A1RXFP1MAPT | |
| SCHEMBL1718386 | 0.82 | KMT2A (0.67) | KMT2AMEN1ALDH1A1RXFP1MAPT | |
| SCHEMBL1719430 | 0.82 | RXFP1 (0.72) | KMT2AMEN1ALDH1A1RXFP1MAPT | |
| SCHEMBL1718651 | 0.82 | RXFP1 (0.78) | KMT2AMEN1ALDH1A1RXFP1MAPT | |
| SCHEMBL1718538 | 0.81 | RXFP1 (0.68) | KMT2AMEN1ALDH1A1RXFP1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1506196-B1 | PYRAZOLOPYRIMIDINES AS SODIUM CHANNEL INHIBITORS | ICAGEN INC (US) | 2012-01-18 | — | — | EP | claimed |
| EP-1506196-B1 | PYRAZOLOPYRIMIDINES AS SODIUM CHANNEL INHIBITORS | ICAGEN INC (US) | 2012-01-18 | — | — | EP | disclosed |