Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 8/20 | 0.46 |
| ▸ | LMNA | P02545 | 5/20 | 0.46 |
| ▸ | TSHR | P16473 | 3/20 | 0.46 |
| ▸ | CNR2 | P34972 | 2/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 4/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 4/20 | 0.37 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.33 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7712510 | 0.85 | SMN1; SMN2 (0.44) | SMN1; SMN2LMNATSHRCNR2CYP1A2 | |
| SCHEMBL187438 | 0.85 | SMN1; SMN2 (0.44) | SMN1; SMN2LMNATSHRCNR2CYP1A2 | |
| SCHEMBL19547562 | 0.85 | SMN1; SMN2 (0.46) | SMN1; SMN2LMNATSHRCNR2CYP1A2 | |
| SCHEMBL15976703 | 0.81 | SMN1; SMN2 (0.45) | SMN1; SMN2LMNATSHRCNR2CYP1A2 | |
| SCHEMBL19560023 | 0.81 | SMN1; SMN2 (0.45) | SMN1; SMN2LMNATSHRCNR2CYP1A2 | |
| Trifluoroacetic Acid SCHEMBL975654 | 0.80 | SMN1; SMN2 (0.43) | SMN1; SMN2LMNATSHRCNR2KDM4E | |
| SCHEMBL8054741 | 0.79 | CNR2 (0.40) | SMN1; SMN2LMNATSHRCNR2CYP1A2 | |
| SCHEMBL12921313 | 0.79 | TUBB4A (0.40) | SMN1; SMN2LMNATSHRCNR2GAA | |
| SCHEMBL8054262 | 0.77 | PPARA (0.42) | SMN1; SMN2LMNATSHRCNR2KDM4E | |
| SCHEMBL975655 | 0.77 | SMN1; SMN2 (0.42) | SMN1; SMN2LMNATSHRCNR2CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2555774-B1 | Medicine combinations containing pde4 inhibitors and ep4 receptor antagonists | BOEHRINGER INGELHEIM INT (DE) | 2015-10-21 | — | — | EP | claimed |