Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOX1 | Q9Y5S8 | 12/20 | 0.55 |
| ▸ | CYBB | P04839 | 2/20 | 0.55 |
| ▸ | NOX3 | Q9HBY0 | 2/20 | 0.55 |
| ▸ | NOX4 | Q9NPH5 | 2/20 | 0.55 |
| ▸ | GAA | P10253 | 7/20 | 0.52 |
| ▸ | MAPT | P10636 | 7/20 | 0.52 |
| ▸ | MEN1 | O00255 | 4/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.52 |
| ▸ | SNCA | P37840 | 4/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.52 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.52 |
| ▸ | BCHE | P06276 | 2/20 | 0.52 |
| ▸ | ACHE | P22303 | 2/20 | 0.52 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.52 |
| ▸ | POLB | P06746 | 1/20 | 0.52 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.52 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.52 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.52 |
| ▸ | MAOA | P21397 | 1/20 | 0.52 |
| ▸ | CNR1 | P21554 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1718554 | 0.87 | NOX1 (0.54) | NOX1CYBBNOX3NOX4GAA | |
| SCHEMBL21550279 | 0.85 | NOX1 (0.53) | NOX1CYBBNOX3NOX4GAA | |
| SCHEMBL1719191 | 0.84 | NOX1 (0.62) | NOX1CYBBNOX3NOX4GAA | |
| SCHEMBL885158 | 0.80 | NOX1 (0.57) | NOX1CYBBNOX3NOX4GAA | |
| SCHEMBL30811565 | 0.79 | NOX1 (0.84) | NOX1CYBBNOX3NOX4GAA | |
| SCHEMBL10372692 | 0.79 | NOX1 (0.84) | NOX1CYBBNOX3NOX4GAA | |
| SCHEMBL18364941 | 0.78 | NOX1 (0.48) | NOX1CYBBNOX3NOX4GAA | |
| SCHEMBL2456413 | 0.78 | SNCA (0.43) | NOX1CYBBNOX3NOX4GAA | |
| SCHEMBL29504844 | 0.78 | SNCA (0.43) | NOX1CYBBNOX3NOX4GAA | |
| SCHEMBL2456416 | 0.76 | CNR2 (0.46) | SNCACNR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8148565-B2 | Method of manufacturing an organic silicon compound that contains a methacryloxy group or an acryloxy group | DOW CORNING TORAY COMPANY, LTD. (JP) | 2012-04-03 | — | — | US | disclosed |
| EP-1915384-B1 | A METHOD OF MANUFACTURING AN ORGANIC SILICON COMPOUND THAT CONTAINS A METHACRYLOXY GROUP OR AN ACRYLOXY GROUP | DOW CORNING TORAY CO LTD (JP) | 2012-01-11 | — | — | EP | disclosed |
| CN-101273049-B | A method of manufacturing an organic silicon compound that contains a methacryloxy group or an acryloxy group | DOW CORNING TORAY CO LTD | 2011-08-17 | — | — | CN | disclosed |
| US-20090306370-A1 | Method Of Manufacturing An Organic Silicon Compound That Contains A Methacryloxy Group Or An Acryloxy Group | DOW TORAY CO., LTD. (JP) | 2009-12-10 | — | — | US | disclosed |
| CN-101273049-A | A method of manufacturing an organic silicon compound that contains a methacryloxy group or an acryloxy group | DOW CORNING TORAY CO LTD (JP) | 2008-09-24 | — | — | CN | disclosed |
| EP-1915384-A1 | A METHOD OF MANUFACTURING AN ORGANIC SILICON COMPOUND THAT CONTAINS A METHACRYLOXY GROUP OR AN ACRYLOXY GROUP | Dow Corning Toray Co., Ltd. (JP) | 2008-04-30 | — | — | EP | disclosed |
| WO-2007020932-A1 | A METHOD OF MANUFACTURING AN ORGANIC SILICON COMPOUND THAT CONTAINS A METHACRYLOXY GROUP OR AN ACRYLOXY GROUP | DOW CORNING TORAY CO., LTD. (JP) | 2007-02-22 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090306370-A1 | Method Of Manufacturing An Organic Silicon Compound That Contains A Methacryloxy Group Or An Acryloxy Group | SIK1, SMS, SIK2 | NOX1 3375/4885CYBB 3891/4885NOX3 3092/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.