Known targets — ChEMBL curated mechanism
CHRM1DRD2DRD3DRD4HDAC1HDAC10HDAC11HDAC2HDAC3HDAC4HDAC5HDAC6HDAC7HDAC8HDAC9HRH1HTR2APDE3ASIGMAR1
The experimentally established mechanism targets of Lactic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 2/20 | 0.69 |
| ▸ | CA5A | P35218 | 1/20 | 0.38 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | GMNN | O75496 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Lactic Acid SCHEMBL2329719 | 0.97 | TP53 (0.73) | TP53CA5ACA5BTSHRSLC7A5 | |
| Lactic Acid SCHEMBL8948925 | 0.94 | TP53 (0.69) | TP53CA5ACA5BTSHRSLC7A5 | |
| Lactic Acid SCHEMBL27886196 | 0.94 | TP53 (0.69) | TP53CA5ACA5BTSHRSLC7A5 | |
| Lactic Acid SCHEMBL3446640 | 0.94 | TP53 (0.69) | TP53CA5ACA5BTSHRSLC7A5 | |
| Lactic Acid SCHEMBL28292938 | 0.94 | TP53 (0.69) | TP53CA5ACA5BTSHRSLC7A5 | |
| Lactic Acid SCHEMBL27678051 | 0.94 | TP53 (0.69) | TP53CA5ACA5BTSHRSLC7A5 | |
| Lactic Acid SCHEMBL1584321 | 0.94 | TP53 (0.69) | TP53CA5ACA5BTSHRSLC7A5 | |
| Lactic Acid SCHEMBL6394823 | 0.94 | TP53 (0.69) | TP53CA5ACA5BTSHRSLC7A5 | |
| Lactic Acid SCHEMBL28286519 | 0.94 | TP53 (0.69) | TP53CA5ACA5BTSHRSLC7A5 | |
| Lactic Acid SCHEMBL367992 | 0.91 | TP53 (0.65) | TP53CA5ACA5BTSHRSLC7A5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10570066-B2 | Agricultural compositions and applications utilizing mineral compounds | RALCO NUTRITION, INC. (US) | 2020-02-25 | — | — | US | disclosed |
| US-20180370866-A1 | AGRICULTURAL COMPOSITIONS AND APPLICATIONS UTILIZING MINERAL COMPOUNDS | RALCO NUTRITION INC (US) | 2018-12-27 | — | — | US | disclosed |
| EP-3131865-A1 | AGRICULTURAL COMPOSITIONS AND APPLICATIONS UTILIZING MINERAL COMPOUNDS | Ralco Nutrition, Inc. (US) | 2017-02-22 | — | — | EP | disclosed |
| US-20150299058-A1 | AGRICULTURAL COMPOSITIONS AND APPLICATIONS UTILIZING MINERAL COMPOUNDS | RALCO NUTRITION, INC. | 2015-10-22 | — | — | US | disclosed |
| WO-2015161269-A1 | AGRICULTURAL COMPOSITIONS AND APPLICATIONS UTILIZING MINERAL COMPOUNDS | RALCO NUTRITION, INC. (US) | 2015-10-22 | — | — | WO | disclosed |