Known targets — ChEMBL curated mechanism
CHRM1DRD2DRD3DRD4HDAC1HDAC10HDAC11HDAC2HDAC3HDAC4HDAC5HDAC6HDAC7HDAC8HDAC9HRH1HTR2APDE3ASIGMAR1
The experimentally established mechanism targets of Lactic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 2/20 | 0.65 |
| ▸ | CA5A | P35218 | 1/20 | 0.35 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | GMNN | O75496 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Lactic Acid SCHEMBL2671202 | 1.00 | TP53 (0.65) | TP53CA5ACA5BTSHRKDM4E | |
| Lactic Acid SCHEMBL5611216 | 0.94 | TP53 (0.65) | TP53CA5ACA5BTSHRKDM4E | |
| Lactic Acid SCHEMBL2329719 | 0.94 | TP53 (0.73) | TP53CA5ACA5BTSHRKDM4E | |
| Lactic Acid SCHEMBL28292938 | 0.91 | TP53 (0.69) | TP53CA5ACA5BTSHRKDM4E | |
| Lactic Acid SCHEMBL17181727 | 0.91 | TP53 (0.69) | TP53CA5ACA5BTSHRKDM4E | |
| Lactic Acid SCHEMBL28286519 | 0.91 | TP53 (0.69) | TP53CA5ACA5BTSHRKDM4E | |
| Lactic Acid SCHEMBL8948925 | 0.91 | TP53 (0.69) | TP53CA5ACA5BTSHRKDM4E | |
| Lactic Acid SCHEMBL1584321 | 0.91 | TP53 (0.69) | TP53CA5ACA5BTSHRKDM4E | |
| Lactic Acid SCHEMBL6394823 | 0.91 | TP53 (0.69) | TP53CA5ACA5BTSHRKDM4E | |
| Lactic Acid SCHEMBL27886196 | 0.91 | TP53 (0.69) | TP53CA5ACA5BTSHRKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1247055-A | Face-care compsns. containing pigment and anti-sweat agent, and application of same composns. | OREAL (FR) | 2000-03-15 | — | — | CN | claimed |
| CN-1246327-A | Cosmetic composite containing pigment, anti-sweat agent and partial cross-linked solid elastic organic polyorganosiloxane and use of the composite | OREAL (FR) | 2000-03-08 | — | — | CN | claimed |
| EP-3801734-A1 | METHODS FOR PROMOTING HAIR GROWTH | Follica, Inc. (US) | 2021-04-14 | — | — | EP | disclosed |
| EP-2648676-A1 | METHODS FOR TREATING BALDNESS AND PROMOTING HAIR GROWTH | Follica, Inc. (US) | 2013-10-16 | — | — | EP | disclosed |
| US-8354096-B2 | Water-free antiperspirant sprays with improved substance | HENKEL AG & CO. KGAA (DE) | 2013-01-15 | — | — | US | disclosed |
| WO-2012078649-A1 | METHODS FOR TREATING BALDNESS AND PROMOTING HAIR GROWTH | FOLLICA, INC. (US) | 2012-06-14 | — | — | WO | disclosed |
| US-20120020906-A1 | ANTIPERSPIRANT SPRAYS WITH ESTER OILS | HENKEL AG & CO. KGAA (DE) | 2012-01-26 | — | — | US | disclosed |
| US-20120014897-A1 | WATER-FREE ANTIPERSPIRANT SPRAYS WITH IMPROVED SUBSTANCE RELEASE | HENKEL AG & CO. KGAA (DE) | 2012-01-19 | — | — | US | disclosed |
| US-20100260698-A1 | Anhydrous Antiperspirant Compositions with Improved Active Substance Release | HENKEL AG & CO. KGAA (DE) | 2010-10-14 | — | — | US | disclosed |
| CN-101610814-A | Low residue antiperspirant stick | HENKEL KGAA (DE) | 2009-12-23 | — | — | CN | disclosed |
| US-20090220444-A1 | Antiperspirant and Deodorant Compositions with Improved Protective Action | HENKEL AG & CO. KGAA (DE) | 2009-09-03 | — | — | US | disclosed |
| WO-2004006883-A1 | SKIN CARE COSMETIC COMPOSITIONS CONTAINING CARBOXYALKYLATES OF BRANCHED ALCOHOLS AND/OR ALKOXYLATES THEREOF | UNILEVER PLC (GB) | 2004-01-22 | — | — | WO | disclosed |
| CN-1247055-A | Face-care compsns. containing pigment and anti-sweat agent, and application of same composns. | OREAL (FR) | 2000-03-15 | — | — | CN | disclosed |
| CN-1246327-A | Cosmetic composite containing pigment, anti-sweat agent and partial cross-linked solid elastic organic polyorganosiloxane and use of the composite | OREAL (FR) | 2000-03-08 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120020906-A1 | ANTIPERSPIRANT SPRAYS WITH ESTER OILS | CUTA, NAPEPLD, LIPE | TP53 3351/4885CA5A 4501/4885CA5B 4740/4885 |
| US-20100260698-A1 | Anhydrous Antiperspirant Compositions with Improved Active Substance Release | CUTA, CYP2W1, IDUA | TP53 4430/4885CA5A 3560/4885CA5B 4210/4885 |
| US-20120014897-A1 | WATER-FREE ANTIPERSPIRANT SPRAYS WITH IMPROVED SUBSTANCE RELEASE | POLR1C, CTRL, CUTA | TP53 1876/4885CA5A 4616/4885CA5B 4773/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.