SCHEMBL17183152

SCHEMBL17183152

C=CCc1cccc2c1ccc1c3ccccc3ccc21

nearest known ligand 0.59

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HPRT1 P00492 3/20 0.52
ALDH1A1 P00352 4/20 0.44
HSD17B10 Q99714 3/20 0.44
TDP1 Q9NUW8 2/20 0.44
CYP2A6 P11509 1/20 0.44
TSHR P16473 1/20 0.44
GABRA1 P14867 1/20 0.43
GABRB2 P47870 1/20 0.43
CYP1A2 P05177 3/20 0.41
CYP2C19 P33261 2/20 0.41
CYP2C9 P11712 1/20 0.41
PAX8 Q06710 1/20 0.39
CYP2D6 P10635 1/20 0.39
HIF1A Q16665 1/20 0.39
CYP1B1 Q16678 1/20 0.39
THRB P10828 1/20 0.39
HPGD P15428 1/20 0.39
MEN1 O00255 1/20 0.38
LMNA P02545 1/20 0.38
KMT2A Q03164 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1147979 1.00 HPRT1 (0.52) HPRT1ALDH1A1HSD17B10TDP1CYP2A6
SCHEMBL30083974 1.00 HPRT1 (0.52) HPRT1ALDH1A1HSD17B10TDP1CYP2A6
Hydrogen Sulfide SCHEMBL28245767 0.98 HPRT1 (0.50) HPRT1ALDH1A1HSD17B10TDP1CYP2A6
SCHEMBL25106 0.88 CYP1A2 (0.52) ALDH1A1TDP1GABRA1GABRB2CYP1A2
SCHEMBL30083984 0.88 CYP1A2 (0.52) ALDH1A1TDP1GABRA1GABRB2CYP1A2
SCHEMBL29106738 0.88 GABRA1 (0.47) HPRT1ALDH1A1HSD17B10TDP1CYP2A6
Piperidine SCHEMBL28096939 0.87 HPRT1 (0.39) HPRT1ALDH1A1HSD17B10TDP1CYP2A6
Water SCHEMBL11405805 0.86 CYP1A2 (0.50) ALDH1A1TDP1GABRA1GABRB2CYP1A2
SCHEMBL249217 0.86 CYP1A2 (0.50) ALDH1A1TDP1GABRA1GABRB2CYP1A2
SCHEMBL1617561 0.86 CYP1A2 (0.50) ALDH1A1TDP1GABRA1GABRB2CYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-111087018-A Crude titanium tetrachloride vanadium removal composition and vanadium removal method 中国石油化工股份有限公司 2020-05-01 CN claimed
US-20150299437-A1 PREPARATION OF RUBBER REINFORCED WITH GRAPHENE AND CARBON NANOTUBES AND FUNCTIONALIZED ELASTOMERS AND TIRE WITH COMPONENT THE GOODYEAR TIRE & RUBBER COMPANY (US) 2015-10-22 US claimed
CN-111087018-A Crude titanium tetrachloride vanadium removal composition and vanadium removal method 中国石油化工股份有限公司 2020-05-01 CN disclosed