Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 3/20 | 0.48 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.48 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.46 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.46 |
| ▸ | RELA | Q04206 | 1/20 | 0.46 |
| ▸ | SCN9A | Q15858 | 3/20 | 0.45 |
| ▸ | ANPEP | P15144 | 3/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.43 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.43 |
| ▸ | LIPE | Q05469 | 1/20 | 0.43 |
| ▸ | NPY1R | P25929 | 1/20 | 0.43 |
| ▸ | KDM1A | O60341 | 1/20 | 0.43 |
| ▸ | MAOB | P27338 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9513864 | 0.87 | EPHX2 (0.51) | DRD2EPHX2NFKB1NFKB2RELA | |
| SCHEMBL9515379 | 0.86 | EPHX2 (0.50) | DRD2EPHX2NFKB1NFKB2RELA | |
| SCHEMBL3375614 | 0.83 | PDE4A (0.52) | DRD2EPHX2 | |
| SCHEMBL30047267 | 0.83 | PDE4A (0.52) | DRD2EPHX2 | |
| SCHEMBL30468602 | 0.83 | PDE4A (0.52) | DRD2EPHX2 | |
| SCHEMBL3375618 | 0.83 | PDE4A (0.52) | DRD2EPHX2 | |
| SCHEMBL1718337 | 0.83 | EPHX2 (0.40) | DRD2EPHX2NFKB1NFKB2RELA | |
| SCHEMBL1718087 | 0.83 | EPHX2 (0.40) | DRD2EPHX2NFKB1NFKB2RELA | |
| SCHEMBL1717979 | 0.82 | ANPEP (0.54) | SCN9AANPEPNPY1R | |
| SCHEMBL2771992 | 0.81 | GAA (0.54) | NFKB1NFKB2RELAGAAKDM1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2084125-B1 | AMINOBENZOCYCLOHEPTENE DERIVATIVES, METHODS FOR PREPARING THE SAME AND USES THEREOF IN THERAPY | UNIV HAUTE ALSACE (FR) | 2012-01-11 | — | — | EP | disclosed |
| EP-2084125-B1 | AMINOBENZOCYCLOHEPTENE DERIVATIVES, METHODS FOR PREPARING THE SAME AND USES THEREOF IN THERAPY | UNIV HAUTE ALSACE (FR) | 2012-01-11 | — | — | EP | disclosed |
| US-20100069504-A1 | AMINOBENZOCYCLOHEPTENE DERIVATIVES, METHODS FOR PREPARING THE SAME AND USES THEREOF IN THERAPY | UNIVERSITE DE HAUTE ALSACE (FR) | 2010-03-18 | — | — | US | disclosed |
| US-20100069504-A1 | AMINOBENZOCYCLOHEPTENE DERIVATIVES, METHODS FOR PREPARING THE SAME AND USES THEREOF IN THERAPY | UNIVERSITE DE HAUTE ALSACE (FR) | 2010-03-18 | — | — | US | disclosed |
| EP-2084125-A1 | AMINOBENZOCYCLOHEPTENE DERIVATIVES, METHODS FOR PREPARING THE SAME AND USES THEREOF IN THERAPY | Universite De Haute Alsace (FR) | 2009-08-05 | — | — | EP | disclosed |
| WO-2008059141-A1 | AMINOBENZOCYCLOHEPTENE DERIVATIVES, METHODS FOR PREPARING THE SAME AND USES THEREOF IN THERAPY | UNIVERSITE DE HAUTE ALSACE (FR) | 2008-05-22 | — | — | WO | disclosed |
| WO-2008059141-A1 | AMINOBENZOCYCLOHEPTENE DERIVATIVES, METHODS FOR PREPARING THE SAME AND USES THEREOF IN THERAPY | UNIVERSITE DE HAUTE ALSACE (FR) | 2008-05-22 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100069504-A1 | AMINOBENZOCYCLOHEPTENE DERIVATIVES, METHODS FOR PREPARING THE SAME AND USES THEREOF IN THERAPY | ANPEP, ENPEP, DNPEP | DRD2 4610/4885EPHX2 346/4885NFKB1 1703/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.