Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PNP | P00491 | 9/20 | 0.75 |
| ▸ | TK1 | P04183 | 1/20 | 0.60 |
| ▸ | XDH | P47989 | 1/20 | 0.57 |
| ▸ | HPRT1 | P00492 | 6/20 | 0.56 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.54 |
| ▸ | USP2 | O75604 | 1/20 | 0.53 |
| ▸ | TSHR | P16473 | 1/20 | 0.53 |
| ▸ | EDNRA | P25101 | 1/20 | 0.53 |
| ▸ | HTR2A | P28223 | 1/20 | 0.53 |
| ▸ | RECQL | P46063 | 1/20 | 0.53 |
| ▸ | BLM | P54132 | 1/20 | 0.53 |
| ▸ | HBB | P68871 | 1/20 | 0.53 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6268532 | 0.97 | PNP (0.79) | PNPTK1XDHHPRT1ADORA2A | |
| Hydrochloric Acid SCHEMBL17186277 | 0.92 | PNP (0.67) | PNPTK1XDHHPRT1USP2 | |
| Hydrochloric Acid SCHEMBL17186404 | 0.90 | PNP (0.72) | PNPTK1XDHHPRT1 | |
| SCHEMBL28757633 | 0.89 | PNP (0.62) | PNPTK1HPRT1USP2TSHR | |
| Hydrochloric Acid SCHEMBL17186460 | 0.89 | PNP (0.63) | PNPTK1XDHHPRT1USP2 | |
| SCHEMBL18249 | 0.86 | PNP (1.00) | PNPTK1XDH | |
| SCHEMBL1980959 | 0.85 | PNP (0.97) | PNPTK1XDH | |
| SCHEMBL17186505 | 0.84 | PNP (0.57) | PNPTK1HPRT1BLM | |
| SCHEMBL17186617 | 0.84 | PNP (0.63) | PNPTK1HPRT1USP2TSHR | |
| SCHEMBL29286376 | 0.84 | TK1 (0.76) | PNPTK1HPRT1USP2TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3131877-A1 | GUANIDINE COMPOUNDS AND USE THEREOF | Immunomet Therapeutics Inc. (US) | 2017-02-22 | — | — | EP | claimed |
| WO-2015160220-A1 | GUANIDINE COMPOUNDS AND USE THEREOF | HANALL BIOPHARMA CO., LTD. (KR) | 2015-10-22 | — | — | WO | claimed |
| EP-3131877-A1 | GUANIDINE COMPOUNDS AND USE THEREOF | Immunomet Therapeutics Inc. (US) | 2017-02-22 | — | — | EP | disclosed |
| WO-2015160220-A1 | GUANIDINE COMPOUNDS AND USE THEREOF | HANALL BIOPHARMA CO., LTD. (KR) | 2015-10-22 | — | — | WO | disclosed |