Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 13/20 | 0.64 |
| ▸ | ALDH1A1 | P00352 | 10/20 | 0.64 |
| ▸ | HTT | P42858 | 6/20 | 0.64 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.64 |
| ▸ | HPGD | P15428 | 11/20 | 0.62 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.62 |
| ▸ | MAPT | P10636 | 4/20 | 0.60 |
| ▸ | GAA | P10253 | 3/20 | 0.60 |
| ▸ | LMNA | P02545 | 4/20 | 0.57 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.57 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.57 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.55 |
| ▸ | MYC | P01106 | 1/20 | 0.53 |
| ▸ | MAX | P61244 | 1/20 | 0.53 |
| ▸ | HSD17B10 | Q99714 | 7/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.52 |
| ▸ | CASP1 | P29466 | 3/20 | 0.52 |
| ▸ | CASP7 | P55210 | 3/20 | 0.52 |
| ▸ | NPC1 | O15118 | 1/20 | 0.52 |
| ▸ | POLB | P06746 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1719095 | 0.85 | KDM4E (0.77) | KDM4EALDH1A1HTTHPGDNPSR1 | |
| SCHEMBL1718295 | 0.84 | KDM4E (0.72) | KDM4EALDH1A1HTTAPOBEC3AHPGD | |
| SCHEMBL4198295 | 0.82 | HPGD (0.67) | KDM4EALDH1A1HTTHPGDNPSR1 | |
| SCHEMBL4198085 | 0.82 | KDM4E (0.64) | KDM4EALDH1A1HTTAPOBEC3AHPGD | |
| SCHEMBL4210280 | 0.82 | KDM4E (0.74) | KDM4EALDH1A1HTTHPGDNPSR1 | |
| SCHEMBL4203278 | 0.82 | HPGD (0.58) | KDM4EALDH1A1HTTHPGDNPSR1 | |
| SCHEMBL4197490 | 0.82 | KDM4E (0.74) | KDM4EALDH1A1HTTAPOBEC3AHPGD | |
| SCHEMBL4212072 | 0.81 | HPGD (0.56) | KDM4EALDH1A1HTTHPGDNPSR1 | |
| SCHEMBL4211598 | 0.81 | TTR (0.64) | KDM4EALDH1A1HTTHPGDNPSR1 | |
| SCHEMBL13167295 | 0.81 | ALDH1A1 (0.75) | KDM4EALDH1A1HTTHPGDNPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1506196-B1 | PYRAZOLOPYRIMIDINES AS SODIUM CHANNEL INHIBITORS | ICAGEN INC (US) | 2012-01-18 | — | — | EP | claimed |
| EP-1506196-B1 | PYRAZOLOPYRIMIDINES AS SODIUM CHANNEL INHIBITORS | ICAGEN INC (US) | 2012-01-18 | — | — | EP | disclosed |