Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.58 |
| ▸ | LMNA | P02545 | 4/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.58 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.58 |
| ▸ | USP2 | O75604 | 2/20 | 0.58 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.57 |
| ▸ | MAPT | P10636 | 4/20 | 0.56 |
| ▸ | THRB | P10828 | 2/20 | 0.56 |
| ▸ | HPGD | P15428 | 4/20 | 0.53 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.53 |
| ▸ | CASP1 | P29466 | 2/20 | 0.53 |
| ▸ | CASP7 | P55210 | 2/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.53 |
| ▸ | HTT | P42858 | 2/20 | 0.53 |
| ▸ | GAA | P10253 | 1/20 | 0.53 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.53 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.51 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1718008 | 0.90 | USP2 (0.72) | MEN1KMT2AALDH1A1LMNAKDM4E | |
| SCHEMBL1719074 | 0.87 | USP2 (0.63) | MEN1KMT2AALDH1A1LMNAKDM4E | |
| SCHEMBL1719378 | 0.86 | USP2 (0.64) | ALDH1A1LMNAKDM4ENPSR1USP2 | |
| SCHEMBL1718598 | 0.85 | USP2 (0.79) | ALDH1A1LMNAKDM4ENPSR1USP2 | |
| SCHEMBL1718333 | 0.83 | USP2 (0.54) | MEN1KMT2AALDH1A1LMNAKDM4E | |
| SCHEMBL3282802 | 0.81 | RXFP1 (0.69) | MEN1KMT2AALDH1A1KDM4EUSP2 | |
| SCHEMBL1718193 | 0.81 | HPGD (0.75) | MEN1KMT2AALDH1A1LMNAKDM4E | |
| SCHEMBL3060904 | 0.80 | RXFP1 (0.67) | MEN1KMT2AALDH1A1KDM4EUSP2 | |
| SCHEMBL3704786 | 0.80 | RXFP1 (0.67) | MEN1KMT2AALDH1A1KDM4EUSP2 | |
| SCHEMBL4203850 | 0.79 | MEN1 (0.85) | MEN1KMT2AALDH1A1LMNAKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1506196-B1 | PYRAZOLOPYRIMIDINES AS SODIUM CHANNEL INHIBITORS | ICAGEN INC (US) | 2012-01-18 | — | — | EP | claimed |
| EP-1506196-B1 | PYRAZOLOPYRIMIDINES AS SODIUM CHANNEL INHIBITORS | ICAGEN INC (US) | 2012-01-18 | — | — | EP | disclosed |