Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LGALS8 | O00214 | 2/20 | 0.56 |
| ▸ | LGALS3 | P17931 | 2/20 | 0.56 |
| ▸ | LGALS4 | P56470 | 2/20 | 0.56 |
| ▸ | SELL | P14151 | 2/20 | 0.49 |
| ▸ | SELP | P16109 | 2/20 | 0.49 |
| ▸ | GJB2 | P29033 | 1/20 | 0.48 |
| ▸ | AKT1 | P31749 | 4/20 | 0.48 |
| ▸ | AKT2 | P31751 | 4/20 | 0.48 |
| ▸ | AKT3 | Q9Y243 | 4/20 | 0.48 |
| ▸ | PIK3R1 | P27986 | 2/20 | 0.48 |
| ▸ | PIK3CA | P42336 | 2/20 | 0.48 |
| ▸ | CETP | P11597 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14666253 | 1.00 | LGALS8 (0.56) | LGALS8LGALS3LGALS4SELLSELP | |
| SCHEMBL23000963 | 0.92 | CETP (0.53) | AKT1AKT2AKT3PIK3R1PIK3CA | |
| SCHEMBL17188245 | 0.92 | CETP (0.53) | AKT1AKT2AKT3PIK3R1PIK3CA | |
| SCHEMBL14666330 | 0.92 | CETP (0.53) | AKT1AKT2AKT3PIK3R1PIK3CA | |
| SCHEMBL19079075 | 0.92 | CETP (0.53) | AKT1AKT2AKT3PIK3R1PIK3CA | |
| SCHEMBL17817032 | 0.92 | CETP (0.53) | AKT1AKT2AKT3PIK3R1PIK3CA | |
| SCHEMBL26236312 | 0.89 | SELL (0.53) | LGALS8LGALS3LGALS4SELLSELP | |
| SCHEMBL25393886 | 0.89 | SELL (0.53) | LGALS8LGALS3LGALS4SELLSELP | |
| SCHEMBL26236311 | 0.89 | SELL (0.53) | LGALS8LGALS3LGALS4SELLSELP | |
| SCHEMBL25391495 | 0.89 | SELL (0.53) | LGALS8LGALS3LGALS4SELLSELP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9161944-B2 | Method for preventing cancer metastasis | INSERM (INSTITUT NATIONAL DE LA SANTE ET DE LA SANTE ET DE LA RECHERCHE MEDICALE) (FR) | 2015-10-20 | — | — | US | disclosed |