Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD11B1 | P28845 | 20/20 | 1.00 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6526139 | 1.00 | HSD11B1 (1.00) | HSD11B1 | |
| SCHEMBL6526144 | 1.00 | HSD11B1 (1.00) | HSD11B1 | |
| SCHEMBL6526147 | 1.00 | HSD11B1 (1.00) | HSD11B1 | |
| SCHEMBL2636362 | 0.89 | HSD11B1 (1.00) | HSD11B1 | |
| SCHEMBL17188556 | 0.89 | HSD11B1 (0.80) | HSD11B1 | |
| SCHEMBL2636357 | 0.89 | HSD11B1 (1.00) | HSD11B1 | |
| SCHEMBL2636360 | 0.89 | HSD11B1 (1.00) | HSD11B1 | |
| SCHEMBL2636600 | 0.89 | HSD11B1 (1.00) | HSD11B1 | |
| SCHEMBL2636599 | 0.89 | HSD11B1 (1.00) | HSD11B1 | |
| SCHEMBL17188434 | 0.89 | HSD11B1 (1.00) | HSD11B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9163012-B2 | Carbamate and urea inhibitors of 11β-hydroxysteroid dehydrogenase 1 | VITAE PHARMACEUTICALS, INC. (US) | 2015-10-20 | — | — | US | disclosed |
| US-9163012-B2 | Carbamate and urea inhibitors of 11β-hydroxysteroid dehydrogenase 1 | VITAE PHARMACEUTICALS, INC. (US) | 2015-10-20 | — | — | US | disclosed |