Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 1/20 | 0.46 |
| ▸ | GRM5 | P41594 | 3/20 | 0.43 |
| ▸ | DRD2 | P14416 | 2/20 | 0.43 |
| ▸ | DRD4 | P21917 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | DRD3 | P35462 | 1/20 | 0.42 |
| ▸ | MAOB | P27338 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.40 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.40 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14085290 | 0.84 | ACHE (0.47) | ACHEGRM5DRD2DRD4DRD3 | |
| SCHEMBL12879342 | 0.82 | ACHE (0.48) | ACHEGRM5DRD2DRD4ALDH1A1 | |
| SCHEMBL10574546 | 0.79 | ACHE (0.42) | ACHEGRM5DRD2DRD4DRD3 | |
| SCHEMBL17188576 | 0.78 | GRM5 (0.49) | ACHEGRM5DRD2DRD4ALDH1A1 | |
| SCHEMBL3982634 | 0.77 | TAAR1 (0.50) | ALDH1A1MAOB | |
| SCHEMBL3246350 | 0.77 | ACHE (0.56) | ACHEDRD2DRD4ALDH1A1DRD3 | |
| SCHEMBL4815490 | 0.77 | MAOB (0.52) | ACHEDRD2DRD4ALDH1A1DRD3 | |
| SCHEMBL756665 | 0.77 | ACHE (0.50) | ACHEDRD2DRD4ALDH1A1DRD3 | |
| SCHEMBL8195129 | 0.77 | ACHE (0.50) | ACHEDRD2DRD4ALDH1A1DRD3 | |
| SCHEMBL7408051 | 0.74 | TAAR1 (0.57) | ACHEDRD2DRD4DRD3POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9161922-B2 | Amine oxidase inhibitors | CASE WESTERN RESERVE UNIVERSITY (US) | 2015-10-20 | — | — | US | disclosed |