Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNMA1 | Q12791 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 3/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | RECQL | P46063 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
| ▸ | F12 | P00748 | 3/20 | 0.40 |
| ▸ | MGAM | O43451 | 2/20 | 0.40 |
| ▸ | AMY1A | P0DUB6 | 2/20 | 0.40 |
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | SI | P14410 | 2/20 | 0.40 |
| ▸ | MGAM2 | Q2M2H8 | 2/20 | 0.40 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.40 |
| ▸ | MIF | P14174 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | PTK2 | Q05397 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 3/20 | 0.38 |
| ▸ | SLC9A1 | P19634 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12204268 | 0.79 | KCNMA1 (0.51) | KCNMA1TSHRNPSR1LMNAKDM4E | |
| SCHEMBL13093779 | 0.75 | KCNMA1 (0.55) | KCNMA1TSHRNPSR1LMNAKDM4E | |
| SCHEMBL2095767 | 0.74 | KDM4E (0.59) | KCNMA1TSHRNPSR1LMNAKDM4E | |
| SCHEMBL2089555 | 0.73 | KCNMA1 (0.50) | KCNMA1TSHRNPSR1LMNAKDM4E | |
| SCHEMBL25862494 | 0.72 | KCNMA1 (0.64) | KCNMA1TSHRNPSR1LMNAKDM4E | |
| SCHEMBL18599169 | 0.72 | KCNMA1 (0.55) | KCNMA1TSHRNPSR1SMN1; SMN2RXFP1 | |
| SCHEMBL3906689 | 0.71 | KCNMA1 (0.63) | KCNMA1TSHRNPSR1LMNASMN1; SMN2 | |
| SCHEMBL8445816 | 0.71 | KCNMA1 (0.62) | KCNMA1TSHRNPSR1LMNASMN1; SMN2 | |
| SCHEMBL21337802 | 0.70 | KCNMA1 (0.47) | KCNMA1TSHRNPSR1LMNAKDM4E | |
| SCHEMBL1938292 | 0.70 | KCNMA1 (0.53) | KCNMA1TSHRNPSR1MGAMAMY1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2932968-A1 | COMPOUND FOR TREATING ALPHA ADRENERGIC MEDIATED CONDITIONS | ALLERGAN, INC. (US) | 2015-10-21 | — | — | EP | disclosed |