SCHEMBL17188948

SCHEMBL17188948

COCc1ccc([C@@H](C)N(C(=O)[C@H]2CNCCO2)C2CC2)cc1CCCN

nearest known ligand 0.70

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
▸ REN P00797 20/20 0.70

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17012956 0.89 REN (0.73) REN
SCHEMBL17013622 0.83 REN (0.95) REN
SCHEMBL16471596 0.82 REN (1.00) REN
SCHEMBL16471509 0.82 REN (1.00) REN
SCHEMBL17188937 0.80 REN (0.85) REN
SCHEMBL17012922 0.80 REN (0.85) REN
SCHEMBL15599615 0.79 REN (0.61) REN
SCHEMBL16471595 0.79 REN (0.78) REN
SCHEMBL16471594 0.79 REN (0.78) REN
SCHEMBL15599850 0.79 REN (0.84) REN

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2933248-A1 NOVEL RENIN INHIBITOR Mitsubishi Tanabe Pharma Corporation (JP) 2015-10-21 — — EP disclosed
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