Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXFP1 | Q9HBX9 | 4/20 | 0.65 |
| ▸ | POLB | P06746 | 2/20 | 0.55 |
| ▸ | MAPT | P10636 | 6/20 | 0.55 |
| ▸ | GAA | P10253 | 1/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.50 |
| ▸ | MEN1 | O00255 | 5/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.49 |
| ▸ | ESR1 | P03372 | 1/20 | 0.49 |
| ▸ | BLM | P54132 | 1/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.49 |
| ▸ | PTGES | O14684 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1718197 | 0.84 | RXFP1 (0.69) | RXFP1POLBMAPTGAAL3MBTL1 | |
| SCHEMBL1719356 | 0.83 | ALDH1A1 (0.71) | RXFP1POLBMAPTGAAKMT2A | |
| SCHEMBL1718201 | 0.83 | MAPT (0.67) | RXFP1POLBMAPTGAAL3MBTL1 | |
| SCHEMBL4200432 | 0.81 | RXFP1 (0.59) | RXFP1POLBMAPTGAAL3MBTL1 | |
| SCHEMBL5658010 | 0.81 | RXFP1 (0.59) | RXFP1POLBMAPTGAAL3MBTL1 | |
| SCHEMBL1718296 | 0.81 | ALDH1A1 (0.75) | RXFP1POLBMAPTGAAL3MBTL1 | |
| SCHEMBL1718651 | 0.80 | RXFP1 (0.78) | RXFP1POLBMAPTGAAL3MBTL1 | |
| SCHEMBL1718369 | 0.79 | RXFP1 (0.59) | RXFP1POLBMAPTGAAL3MBTL1 | |
| SCHEMBL1718964 | 0.79 | RXFP1 (1.00) | RXFP1POLBMAPTKMT2AMEN1 | |
| SCHEMBL1718426 | 0.79 | MAPT (0.62) | RXFP1POLBMAPTGAAL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1506196-B1 | PYRAZOLOPYRIMIDINES AS SODIUM CHANNEL INHIBITORS | ICAGEN INC (US) | 2012-01-18 | — | — | EP | claimed |
| EP-1506196-B1 | PYRAZOLOPYRIMIDINES AS SODIUM CHANNEL INHIBITORS | ICAGEN INC (US) | 2012-01-18 | — | — | EP | disclosed |