SCHEMBL17189010

SCHEMBL17189010

CCCCCOc1cc([C@@H](C)N(C(=O)[C@H]2CNCCO2)C2CC2)cc2c1OCCC2

nearest known ligand 0.78

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
▸ REN P00797 20/20 0.78

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15599643 0.92 REN (0.91) REN
SCHEMBL16478448 0.87 REN (1.00) REN
SCHEMBL16478449 0.87 REN (1.00) REN
SCHEMBL16360160 0.87 REN (1.00) REN
SCHEMBL15435781 0.77 REN (0.86) REN
SCHEMBL16471488 0.76 REN (1.00) REN
SCHEMBL16471489 0.76 REN (1.00) REN
SCHEMBL16360455 0.76 REN (0.85) REN
SCHEMBL12525603 0.76 REN (0.86) REN
SCHEMBL15435699 0.76 REN (0.74) REN

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2933248-A1 NOVEL RENIN INHIBITOR Mitsubishi Tanabe Pharma Corporation (JP) 2015-10-21 — — EP disclosed
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