SCHEMBL17189012

SCHEMBL17189012

CC(C)c1cc([C@@H](C)N(C(=O)[C@H]2CNCCO2)C2CC2)cc(CCCNO)n1

nearest known ligand 0.68

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
▸ REN P00797 20/20 0.68

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17012958 0.90 REN (0.84) REN
SCHEMBL15599931 0.90 REN (0.68) REN
SCHEMBL17012964 0.87 REN (0.73) REN
SCHEMBL15599867 0.87 REN (0.63) REN
SCHEMBL19526713 0.83 REN (0.70) REN
SCHEMBL15417909 0.82 REN (0.85) REN
SCHEMBL17012960 0.82 REN (0.86) REN
SCHEMBL16471603 0.81 REN (1.00) REN
SCHEMBL17012957 0.81 REN (0.85) REN
SCHEMBL19526838 0.81 REN (0.88) REN

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2933248-A1 NOVEL RENIN INHIBITOR Mitsubishi Tanabe Pharma Corporation (JP) 2015-10-21 — — EP disclosed
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