SCHEMBL1718902

SCHEMBL1718902

[CH2]c1ccc(C(C)(C)CC)cc1

nearest known ligand 0.60

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
NPC1 O15118 3/20 0.48
RAB9A P51151 3/20 0.48
MAPT P10636 1/20 0.48
LMNA P02545 1/20 0.41
MAPK1 P28482 1/20 0.41
CASP3 P42574 1/20 0.41
ATM Q13315 1/20 0.41
SMN1; SMN2 Q16637 1/20 0.41
SENP8 Q96LD8 1/20 0.41
SENP7 Q9BQF6 1/20 0.41
SENP6 Q9GZR1 1/20 0.41
CNR2 P34972 2/20 0.40
HRH3 Q9Y5N1 12/20 0.39
MAOB P27338 8/20 0.39
SHBG P04278 1/20 0.37
POLB P06746 1/20 0.37
CYP2C9 P11712 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL779443 0.87 NPC1 (0.58) NPC1RAB9AMAPTLMNAMAPK1
SCHEMBL3292125 0.79 NPC1 (0.52) NPC1RAB9AMAPTLMNAMAPK1
SCHEMBL5552840 0.79 NPC1 (0.52) NPC1RAB9AMAPTLMNAMAPK1
SCHEMBL3625528 0.79 NPC1 (0.52) NPC1RAB9AMAPTLMNAMAPK1
SCHEMBL1718278 0.78 SHBG (0.61) NPC1RAB9AMAPTLMNAMAPK1
SCHEMBL21791678 0.77 NPC1 (0.50) NPC1RAB9AMAPTLMNAMAPK1
SCHEMBL2230579 0.77 TSHR (0.55) NPC1RAB9AMAPTLMNAMAPK1
SCHEMBL13016 0.77 NPC1 (0.50) NPC1RAB9AMAPTLMNAMAPK1
SCHEMBL1718279 0.76 CNR2 (0.56) CNR2
SCHEMBL15294399 0.75 NPC1 (0.48) NPC1RAB9AMAPTLMNAMAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 37 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6030978-A EXHIBIT FUNGICIDAL EFFECT OR GROWTH-INHIBITORY EFFECT AGAINST FUNGI INCLUDING CUTANEOUS FILAMENTOUS FUNGUS, SUCH AS EPIDERMOPHYTON, MICROSPORUM, TRICHOPHYTON, SPOROTHRIX SCHENCKII, ASPERGILLUS OR CANDIDA; NONTOXICITY; HANWHA CORPORATION (KR) 2000-02-29 US claimed
US-6008356-A BRBERINE SALT DERIVATIVE IS REACTED WITH SODIUM TETRABORATE AND POTASSIUM CARBONATE IN ALCOHOL SOLVEANT TO FORM INTERMEDIATE, REACTING INTERMEDIATE WITH ALKYL SUBSTITUENT IN ACETONITRILE SOLVENT, OXIDIZING THE FORMED INTERMEDIATE HANWHA CORPORATION (KR) 1999-12-28 US claimed
CN-111315828-B Composition, cured product, optical filter, and method for producing cured product 株式会社艾迪科 2023-09-29 CN disclosed
CN-112154167-B Composition, cured product, optical filter, and method for producing cured product 株式会社艾迪科 2023-08-22 CN disclosed
CN-112154167-A Composition, cured product, optical filter, and method for producing cured product 株式会社艾迪科 2020-12-29 CN disclosed
CN-111315828-A Composition, cured product, optical filter, and method for producing cured product 株式会社艾迪科 2020-06-19 CN disclosed
WO-2020021969-A1 COMPOSITION, CURED PRODUCT, OPTICAL FILTER, AND PRODUCTION METHOD FOR CURED PRODUCT 株式会社ADEKA 2020-01-30 WO disclosed
EP-1952982-B1 Radiation-curable polymerizable composition, ink composition, inkjet recording method, printed material, planographic printing plate, and method for forming planographic printing plate FUJIFILM CORP (JP) 2015-05-06 EP disclosed
EP-2169018-B1 Ink composition and inkjet recording method FUJIFILM CORP (JP) 2012-01-18 EP disclosed
EP-2169022-B1 Ink composition and inkjet recording method FUJIFILM CORP (JP) 2011-11-16 EP disclosed
WO-2011132113-A2 MERCURY- AND SCANDIUM - FREE HIGH INTENSITY GAS - DISCHARGE LAMP KONINKLIJKE PHILIPS ELECTRONICS N.V. (NL) 2011-10-27 WO disclosed
EP-0369335-B1 2-Aminodecaline derivatives and their use BASF AG (DE) 1994-02-23 EP disclosed
US-5281625-A Benzyl substituted guanidine derivatives, salts, and metal complexes BASF AKTIENGESELLSCHAFT (DE) 1994-01-25 US disclosed
EP-0534501-A2 Fungicidal guanidines BASF Aktiengesellschaft (DE) 1993-03-31 EP disclosed
US-5126374-A For plants, seeds, soils, effective at low concentrations BASF AKTIENGESELLSCHAFT (DE) 1992-06-30 US disclosed
US-5051409-A Fungicides BASF AKTIENGESELLSCHAFT (DE) 1991-09-24 US disclosed
US-5032616-A Plants TRACOR, INC. 1991-07-16 US disclosed
EP-0406699-A2 Fungicidal guanidines BASF Aktiengesellschaft (DE) 1991-01-09 EP disclosed
EP-0369335-A2 2-Aminodecaline derivatives and their use BASF Aktiengesellschaft (DE) 1990-05-23 EP disclosed
US-4218370-A POLYMERIZATION CATALYST, CROSSLINKING, HOMO- OR COPOLYMER IN ADDITION POLYMERIZATION PENNWALT CORPORATION (US) 1980-08-19 US disclosed