SCHEMBL17189034

SCHEMBL17189034

CCCc1nc([C@@H](C)N(C(=O)[C@H]2CNCCO2)C2CC2)cc2c1ccn2CCCO

nearest known ligand 0.61

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
▸ REN P00797 20/20 0.61

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15599627 0.92 REN (0.73) REN
SCHEMBL15599658 0.86 REN (0.75) REN
SCHEMBL17012933 0.81 REN (0.77) REN
SCHEMBL17012992 0.81 REN (0.57) REN
SCHEMBL17012980 0.81 REN (0.76) REN
SCHEMBL17012981 0.80 REN (0.75) REN
SCHEMBL17189042 0.79 REN (0.51) REN
SCHEMBL12525994 0.78 REN (0.85) REN
SCHEMBL15599919 0.77 REN (0.58) REN
SCHEMBL15435687 0.76 REN (1.00) REN

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2933248-A1 NOVEL RENIN INHIBITOR Mitsubishi Tanabe Pharma Corporation (JP) 2015-10-21 — — EP disclosed
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