SCHEMBL17189040

SCHEMBL17189040

CONCCCn1cc([C@@H](C)N(C(=O)[C@H]2CNCCO2)C2CC2)nc1C1CCOCC1

nearest known ligand 0.54

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
▸ REN P00797 20/20 0.54

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17013100 0.92 REN (0.65) REN
SCHEMBL15599934 0.92 REN (0.52) REN
SCHEMBL17012921 0.86 REN (0.65) REN
SCHEMBL15599732 0.84 REN (0.56) REN
SCHEMBL17005415 0.84 REN (0.55) REN
SCHEMBL17013742 0.80 REN (0.50) REN
SCHEMBL15599758 0.80 REN (0.42) REN
SCHEMBL17013020 0.79 REN (0.68) REN
SCHEMBL17013696 0.79 REN (0.67) REN
SCHEMBL17013046 0.79 REN (0.67) REN

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2933248-A1 NOVEL RENIN INHIBITOR Mitsubishi Tanabe Pharma Corporation (JP) 2015-10-21 — — EP disclosed
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