SCHEMBL17189057

SCHEMBL17189057

CONCCCc1cc([C@@H](C)N(C(=O)[C@H]2CNCCO2)C2CC2)cnc1C1CCOCC1

nearest known ligand 0.66

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
▸ REN P00797 20/20 0.66

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17189022 0.95 REN (0.67) REN
SCHEMBL17013116 0.92 REN (0.79) REN
SCHEMBL15599668 0.92 REN (0.79) REN
SCHEMBL15599649 0.88 REN (0.70) REN
SCHEMBL17189047 0.88 REN (0.70) REN
SCHEMBL17012984 0.87 REN (0.80) REN
SCHEMBL15599615 0.83 REN (0.61) REN
SCHEMBL16471601 0.81 REN (0.82) REN
SCHEMBL16471600 0.81 REN (0.82) REN
SCHEMBL17013115 0.80 REN (0.83) REN

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2933248-A1 NOVEL RENIN INHIBITOR Mitsubishi Tanabe Pharma Corporation (JP) 2015-10-21 — — EP disclosed
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