SCHEMBL17189065

SCHEMBL17189065

CCc1nc(CN(C(=O)[C@H]2CN[C@@H](COC)CO2)C2CC2)cc2c1ncn2CCCOC

nearest known ligand 0.43

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
▸ REN P00797 20/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15599655 0.91 REN (0.44) REN
SCHEMBL17013144 0.85 REN (0.56) REN
SCHEMBL17013792 0.76 REN (0.58) REN
SCHEMBL17189064 0.72 REN (0.53) REN
SCHEMBL17013729 0.71 REN (0.74) REN
SCHEMBL17013145 0.70 REN (0.57) REN
SCHEMBL17013736 0.68 REN (0.58) REN
SCHEMBL15599674 0.68 PDGFRA (0.35) —
SCHEMBL13131714 0.67 REN (0.76) REN
SCHEMBL13131682 0.64 REN (0.73) REN

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2933248-A1 NOVEL RENIN INHIBITOR Mitsubishi Tanabe Pharma Corporation (JP) 2015-10-21 — — EP disclosed
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