Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | ERN1 | O75460 | 2/20 | 0.37 |
| ▸ | ATM | Q13315 | 1/20 | 0.37 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.36 |
| ▸ | MTNR1A | P48039 | 3/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.35 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | RELA | Q04206 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 2/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.34 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9786092 | 0.86 | AOC3 (0.47) | KDM4EERN1HSP90AA1ALDH1A1MEN1 | |
| SCHEMBL3273390 | 0.78 | KCNJ1 (0.45) | KDM4EERN1MTNR1AALDH1A1MEN1 | |
| SCHEMBL6851211 | 0.76 | TDP1 (0.41) | ALDH1A1MEN1LMNAKMT2ASMN1; SMN2 | |
| SCHEMBL19380526 | 0.75 | KDM4E (0.49) | KDM4EATMMTNR1AALDH1A1MEN1 | |
| SCHEMBL1494402 | 0.75 | LMNA (0.36) | ALDH1A1MEN1LMNAKMT2AHPGD | |
| SCHEMBL77894 | 0.75 | KDM4E (0.44) | KDM4EATMMTNR1AALDH1A1LMNA | |
| SCHEMBL3216500 | 0.74 | KDM4E (0.40) | KDM4EERN1ALDH1A1MEN1LMNA | |
| SCHEMBL21262188 | 0.74 | ERN1 (0.44) | KDM4EERN1MTNR1AALDH1A1HPGD | |
| SCHEMBL17397861 | 0.74 | KDM4E (0.40) | KDM4EERN1MTNR1AALDH1A1MEN1 | |
| SCHEMBL6851157 | 0.74 | TDP1 (0.46) | KDM4EERN1ALDH1A1MEN1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1744619-B1 | MUTANT RECEPTORS AND THEIR USE IN A NUCLEAR RECEPTOR-BASED INDUCIBLE GENE EXPRESSION SYSTEM | INTREXON CORP (US) | 2015-10-21 | — | — | EP | disclosed |