Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 5/20 | 0.68 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.65 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.65 |
| ▸ | HPGD | P15428 | 4/20 | 0.65 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.65 |
| ▸ | LMNA | P02545 | 3/20 | 0.63 |
| ▸ | MAPT | P10636 | 3/20 | 0.63 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.63 |
| ▸ | MEN1 | O00255 | 1/20 | 0.60 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.60 |
| ▸ | POLB | P06746 | 1/20 | 0.57 |
| ▸ | RAB9A | P51151 | 1/20 | 0.57 |
| ▸ | GAA | P10253 | 2/20 | 0.55 |
| ▸ | HTT | P42858 | 1/20 | 0.55 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.55 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1717975 | 0.91 | TP53 (0.83) | TP53KDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL1718576 | 0.86 | TP53 (0.65) | TP53KDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL8192027 | 0.86 | TP53 (0.65) | TP53KDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL4737183 | 0.85 | TP53 (0.80) | TP53KDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL8202423 | 0.83 | TP53 (0.77) | TP53KDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL1718594 | 0.83 | TP53 (0.70) | TP53KDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL4731862 | 0.82 | KDM4E (0.80) | TP53KDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL1718453 | 0.82 | HPGD (0.80) | TP53KDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL1718608 | 0.80 | MAPT (0.73) | TP53KDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL8191835 | 0.80 | TP53 (0.77) | TP53KDM4EALDH1A1HPGDHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1506196-B1 | PYRAZOLOPYRIMIDINES AS SODIUM CHANNEL INHIBITORS | ICAGEN INC (US) | 2012-01-18 | — | — | EP | claimed |