⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17189767 | 1.00 | — | — | |
| SCHEMBL24730700 | 0.87 | L3MBTL1 (0.31) | — | |
| SCHEMBL24730812 | 0.87 | L3MBTL1 (0.31) | — | |
| SCHEMBL24730701 | 0.87 | L3MBTL1 (0.31) | — | |
| SCHEMBL23177885 | 0.76 | PIK3CD (0.31) | — | |
| SCHEMBL21716084 | 0.76 | PIK3CD (0.31) | — | |
| SCHEMBL23178018 | 0.76 | PIK3CD (0.31) | — | |
| SCHEMBL14591901 | 0.76 | PIK3CD (0.31) | — | |
| SCHEMBL24754120 | 0.76 | PIK3CD (0.31) | — | |
| SCHEMBL23177932 | 0.76 | PIK3CD (0.31) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240226113-A1 | HETEROCYCLIC COMPOUNDS AND USES THEREOF | KUMQUAT BIOSCIENCES INC. | 2024-07-11 | — | — | US | disclosed |
| US-9926299-B2 | Inhibitors of bruton's tyrosine kinase | CENTAURUS BIOPHARMA CO., LTD. (CN) | 2018-03-27 | — | — | US | disclosed |
| US-20170144986-A1 | INHIBITOR OF BRUTON'S TYROSINE KINASE | CENTAURUS BIOPHARMA CO., LTD. (CN) | 2017-05-25 | — | — | US | disclosed |
| US-20150299171-A1 | INHIBITORS OF BRUTON'S TYROSINE KINASE | CENTAURUS BIOPHARMA CO., LTD. (CN) | 2015-10-22 | — | — | US | disclosed |